Importance DNA methylation may play an important role in schizophrenia (SZ), either
directly as a mechanism of pathogenesis or as a biomarker of risk. Objective To scan …

We performed a systematic analysis of blood DNA methylation profiles from 4483
participants from seven independent cohorts identifying differentially methylated positions …

Background Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by
episodic psychosis and altered cognitive function. Despite success in identifying genetic …

Importance Epigenetic studies present unique opportunities to advance schizophrenia
research because they can potentially account for many of its clinical features and suggest …

Genetic association studies provide evidence for a substantial polygenic component to
schizophrenia, although the neurobiological mechanisms underlying the disorder remain …

DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of
gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed …

Importance Schizophrenia is a severe mental disorder in which epigenetic mechanisms may
contribute to illness risk. Epigenetic profiles can be derived from blood cells, but to our …

Emerging evidence suggests that schizophrenia (SZ) susceptibility involves variation at
genetic, epigenetic and transcriptome levels. We describe an integrated approach that …

Schizophrenia is a severe psychiatric disease affecting about 1% of the world's population,
with significant effects on patients and society. Genetic studies have identified several …

Schizophrenia (SCZ) is a complex psychiatric disease with a lifetime morbidity rate of 0.5–
1.0%. To date, aberrant DNA methylation in SCZ has been reported in several studies …