Mammalian folliculogenesis and oocyte physiology are complex and not fully understood.
However, major advances over the past 15 years in our ability to create and study in vivo …

The pool of primordial follicles in humans is laid down during embryonic development and
follicles can remain dormant for prolonged intervals, often decades, until individual follicles …

The identification of genes and deduced pathways from the mature human oocyte can help
us better understand oogenesis, folliculogenesis, fertilization, and embryonic development …

The oocyte is a key regulator of ovarian folliculogenesis and early embryonic development.
However, the composition of the oocyte transcriptome and identities and functions of key …

Functional ovarian cells are essential for human fertility. In the adult ovary, different cell
types ensure ovary homeostasis, enable hormonal production, and support oocyte …

Ovarian oogenesis and folliculogenesis are complex and coordinated biological processes
which require a series of events that induce morphological and functional changes within …

Female infertility syndromes are among the most prevalent chronic health disorders in
women, but their genetic basis remains unknown because of uncertainty regarding the …

Background The successful achievement of early ovarian folliculogenesis is important for
fertility and reproductive life span. This complex biological process requires the appropriate …

Within the development of ovarian follicle, in addition to cell proliferation and differentiation,
sophisticated cell–cell cross talks are established among follicular somatic cells such as …

The development and maturation of follicles is a sophisticated and multistage process. The
dynamic gene expression of oocytes and the surrounding somatic cells and the dialogs …