Thyroid hormone therapy in differentiated thyroid cancer

G Grani, V Ramundo, A Verrienti, M Sponziello… - Endocrine, 2019 - Springer
Surgery—with or without postoperative radioiodine—is the standard of care for most patients
with differentiated thyroid carcinoma (DTC). Thyroid hormone replacement therapy is the …

Differentiated thyroid cancer: a focus on post-operative thyroid hormone replacement and thyrotropin suppression therapy

BJ Gigliotti, S Jasim - Endocrine, 2024 - Springer
Purpose This review focuses on post-operative thyroid hormone replacement and
thyrotropin suppression therapy in patients with differentiated thyroid cancer. Methods A …

Thyroid stimulating hormone suppression in the long-term follow-up of differentiated thyroid cancer

B Freudenthal, GR Williams - Clinical Oncology, 2017 - Elsevier
Differentiated thyroid cancer is the most common form of thyroid cancer and its prognosis is
favourable in most cases. Suppression of thyroid stimulating hormone (TSH) by supra …

Thyrotropin suppressive therapy in thyroid carcinoma: what are the targets?

G Brabant - The Journal of Clinical Endocrinology & Metabolism, 2008 - academic.oup.com
Published guidelines on the treatment of thyroid carcinoma support TSH suppressive
therapy as the standard of care for long-term follow-up after initial surgery and sequential …

Thyrotropin suppression and disease progression in patients with differentiated thyroid cancer: results from the National Thyroid Cancer Treatment Cooperative …

DS Cooper, B Specker, M Ho, M Sperling… - Thyroid, 1998 - liebertpub.com
The ideal therapy for differentiated thyroid cancer is uncertain. Although thyroid hormone
treatment is pivotal, the degree of thyrotropin (TSH) suppression that is required to prevent …

Effects of thyroid hormone suppression therapy on adverse clinical outcomes in thyroid cancer

NJ McGriff, G Csako, L Gourgiotis, LC Guthrie… - Annals of …, 2002 - Taylor & Francis
BACKGROUND. Long-term thyroid hormone (TH) therapy aiming at the suppression of
serum thyrotropin (TSH) has been traditionally used in the management of well differentiated …

Benefits of thyrotropin suppression versus the risks of adverse effects in differentiated thyroid cancer

B Biondi, DS Cooper - Thyroid, 2010 - liebertpub.com
Background: Despite clinical practice guidelines for the management of differentiated thyroid
cancer (DTC), there are no recommendations on the optimal serum thyrotropin (TSH) …

Thyrotropin suppression increases the risk of osteoporosis without decreasing recurrence in ATA low-and intermediate-risk patients with differentiated thyroid …

LY Wang, AW Smith, FL Palmer, RM Tuttle, A Mahrous… - Thyroid, 2015 - liebertpub.com
Background: Levothyroxine suppression of thyrotropin (TSH) is broadly applied to patients
with thyroid cancer despite lack of consensus on the optimal TSH concentration necessary …

Does postoperative thyrotropin suppression therapy truly decrease recurrence in papillary thyroid carcinoma? A randomized controlled trial

I Sugitani, Y Fujimoto - The Journal of Clinical Endocrinology & …, 2010 - academic.oup.com
Context: TSH suppression therapy has been used to decrease thyroid cancer recurrence.
However, validation of effects through studies providing a high level of evidence has been …

Contemporary post surgical management of differentiated thyroid carcinoma

H Tala, RM Tuttle - Clinical Oncology, 2010 - Elsevier
Risk assessment is the cornerstone of contemporary management of thyroid cancer.
Following thyroid surgery, an initial risk assessment of recurrence and disease-specific …