[PDF][PDF] Rutin Ameliorates Hepatic Fibrosis via Targeting Hepatic Stellate Cells' Activation, Proliferation and Apoptosis
M Safar - 2021 - buescholar.bue.edu.eg
Despite rutin, extracted from black mulberry, has several pharmacological activities, its exact
effect against hepatic fibrosis remains incompletely identified. Accordingly, this study …
effect against hepatic fibrosis remains incompletely identified. Accordingly, this study …
Rutin ameliorates hepatic fibrosis via targeting hepatic stellate cells' activation, proliferation and apoptosis
WH El-Maadawy, SH Seif el-Din, SM Ezzat… - Journal of Herbs …, 2021 - Taylor & Francis
Despite rutin, extracted from black mulberry, has several pharmacological activities, its exact
effect against hepatic fibrosis remains incompletely identified. Accordingly, this study …
effect against hepatic fibrosis remains incompletely identified. Accordingly, this study …
Tricetin protects against liver fibrosis through promoting autophagy and Nrf2 signaling in hepatic stellate cells
W Li, R Lv, T Zou, M Chen - Life Sciences, 2024 - Elsevier
Aims The study aims to investigate the role and underlying mechanisms of tricetin in
regulating hepatic stellate cells (HSCs) activation. Main methods We treated human hepatic …
regulating hepatic stellate cells (HSCs) activation. Main methods We treated human hepatic …
Bromelain mitigates liver fibrosis via targeting hepatic stellate cells in vitro and in vivo
Various therapeutic approaches are conducted for regression of liver fibrosis and prevent
possible further carcinogenic transformation. This study was aimed to assess the …
possible further carcinogenic transformation. This study was aimed to assess the …
[HTML][HTML] Rutin mitigates hepatic fibrogenesis and inflammation through targeting TLR4 and P2X7 receptor signaling pathway in vitro and in vivo
LS Hou, ZY Cui, P Sun, HQ Piao, X Han, J Song… - Journal of Functional …, 2020 - Elsevier
Rutin is a flavonol glycoside widely existing in plants, used as food antioxidant and
nutritional enhancer. Rutin has vitamin P-like effect and anti-inflammatory effect. This study …
nutritional enhancer. Rutin has vitamin P-like effect and anti-inflammatory effect. This study …
[HTML][HTML] Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis
NM El-Lakkany, WH El-Maadawy, SHS El-Din… - Asian Pacific journal of …, 2017 - Elsevier
Objective To investigate the antifibrotic role of rosmarinic acid (RA), a natural polyphenolic
compound, on HSCs activation/proliferation and apoptosis in vitro and in vivo. Methods The …
compound, on HSCs activation/proliferation and apoptosis in vitro and in vivo. Methods The …
Antifibrotic effects of luteolin on hepatic stellate cells and liver fibrosis by targeting AKT/mTOR/p70S6K and TGFβ/Smad signalling pathways
J Li, X Li, W Xu, S Wang, Z Hu, Q Zhang… - Liver …, 2015 - Wiley Online Library
Abstract Background & Aims Luteolin has been reported to exert antifibrogenic effects in CC
l4‐induced hepatic fibrosis in mice. However, limited information is available on the cellular …
l4‐induced hepatic fibrosis in mice. However, limited information is available on the cellular …
[HTML][HTML] Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway
L Zhou, X Dong, L Wang, L Shan, T Li, W Xu, Y Ding… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Although many advances have been made in understanding the pathogenesis of liver
fibrosis, few options are available for treatment. Casticin, one of the major flavonoids in …
fibrosis, few options are available for treatment. Casticin, one of the major flavonoids in …
[PDF][PDF] Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis
Objective: To investigate the antifibrotic role of rosmarinic acid (RA), a natural polyphenolic
compound, on HSCs activation/proliferation and apoptosis in vitro and in vivo. Methods: The …
compound, on HSCs activation/proliferation and apoptosis in vitro and in vivo. Methods: The …
Scoparone attenuates hepatic stellate cell activation through inhibiting TGF-β/Smad signaling pathway
X Liu, X Zhao - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Activation of hepatic stellate cells (HSCs) plays a critical role in liver fibrosis. Scoparone, a
major constituent isolated from Artemisia capillaris, was reported to possess …
major constituent isolated from Artemisia capillaris, was reported to possess …