Congenital nephrogenic diabetes insipidus is a recessive hereditary disorder characterized
by the inability of the kidney to concentrate urine in response to vasopressin. Recently, we …

The main water channel of the brain, aquaporin-4 (AQP4), is one of the classical water-
specific aquaporins. It is expressed in many epithelial tissues in the basolateral membrane …

Aquaporins (AQP) are family of water channels found in several epithelial and endothelial
cells, whose recent identification has provided insights into water transport in several …

The aquaporins (AQPs) are a family of water-transporting proteins that are broadly
expressed in mammalian cells. Two AQPs in the central nervous system, AQP1 and AQP4 …

The regulation of water balance in the brain is crucial. A disruption in this equilibrium causes
an increase in brain water content that significantly contributes to the pathophysiology of …

The glial water channel aquaporin‐4 (AQP4) has been hypothesized to modulate water and
potassium fluxes associated with neuronal activity. In this study, we examined the seizure …

The recent discovery of aquaporins, a family of highly conserved water channel proteins,
which are expressed in both eukaryotes and prokaryotes, has provoked a re-evaluation of …

Five single-point aquaporin-2 (AQP2) mutations that cause non-X-linked nephrogenic
diabetes insipidus (NDI) were characterized to establish the cellular defect and to develop …

Abstract Aquaporin 1 (AQP1) is a member of a family of small, integral membrane water-
transporting proteins, which facilitate water movement across cell membranes in response to …