Continuous remote ischemic conditioning attenuates cognitive and motor deficits from moderate traumatic brain injury

V Pandit, M Khan, TM Largent-Milnes… - Journal of Trauma …, 2018 - journals.lww.com
BACKGROUND While studies show that single-dose remote ischemic conditioning (RIC)
improves outcomes, the effect of continuous (daily) RIC is unknown. Thus, we aimed to …

Remote ischemic conditioning preserves cognition and motor coordination in a mouse model of traumatic brain injury

AJ Sandweiss, A Azim, K Ibraheem… - Journal of Trauma …, 2017 - journals.lww.com
METHODS We subjected 100 male C57BL mice to a closed-skull cortical-controlled impact
injury. Two hours after the TBI, the animals were allocated to either the RIC group (n= 50) or …

Secondary brain injury in trauma patients: the effects of remote ischemic conditioning

B Joseph, V Pandit, B Zangbar… - Journal of Trauma …, 2015 - journals.lww.com
BACKGROUND Management of traumatic brain injury (TBI) is focused on preventing
secondary brain injury. Remote ischemic conditioning (RIC) is an established treatment …

Remote Ischemic Conditioning for Motor Recovery after Acute Ischemic Stroke

W Yu, C Ren, J Du, W Zhao, W Guo, X Ji - The Neurologist, 2023 - journals.lww.com
Background: Remote ischemic conditioning (RIC) has shown an impressive neuroprotective
effect on acute ischemic stroke (AIS) in animal experiments. But whether chronic RIC …

Per-and post-remote ischemic conditioning attenuates ischemic brain injury via inhibition of the TLR4/MyD88 signaling pathway in aged rats

J Lv, W Yan, J Zhou, H Pei, R Zhao - Experimental Brain Research, 2021 - Springer
Remote ischemic conditioning (RIC), as an emerging protective method, might be used
clinically to prevent ischemia–reperfusion injury (IRI) in ischemic stroke. In this study, we aim …

Remote ischemic conditioning and stroke recovery

MW McDonald, A Dykes, MS Jeffers… - … and Neural Repair, 2021 - journals.sagepub.com
Remote ischemic conditioning (RIC) is a noninvasive procedure whereby several periods of
ischemia are induced in a limb. Although there is growing interest in using RIC to improve …

Remote Ischemic Conditioning After Stroke Trial 2: A Phase II b Randomized Controlled Trial in Hyperacute Stroke

TJ England, A Hedstrom, SE O'Sullivan… - Journal of the …, 2019 - Am Heart Assoc
Background Repeated episodes of limb ischemia and reperfusion (remote ischemic
conditioning [RIC]) may protect the brain from ischemic reperfusion injury. Methods and …

Short‐term remote ischemic conditioning may protect monkeys after ischemic stroke

L Guo, DA Zhou, DI Wu, J Ding, X He… - Annals of Clinical …, 2019 - Wiley Online Library
Objective We aimed to evaluate the safety and effectiveness of short‐term remote ischemic
postconditioning (RIPC) in acute stroke monkey models. Methods Acute stroke monkeys …

[HTML][HTML] Neuroprotection by remote ischemic conditioning in the setting of acute ischemic stroke: a preclinical two-centre study

MV Basalay, M Wiart, F Chauveau, C Dumot, C Leon… - Scientific Reports, 2020 - nature.com
Reperfusion is the only existing strategy for patients with acute ischemic stroke, however it
causes further brain damage itself. A feasible therapy targeting reperfusion injury is remote …

Neuroprotection by remote ischemic conditioning in rodent models of focal ischemia: a systematic review and meta-analysis

AJ Ripley, MS Jeffers, MW McDonald, J Montroy… - Translational Stroke …, 2021 - Springer
Remote ischemic conditioning (RIC) is a promising neuroprotective therapy for ischemic
stroke. Preclinical studies investigating RIC have shown RIC reduced infarct volume, but …