The feasibility of spatial frequency domain imaging (SFDI) for breast surgical margin
assessment was evaluated in tissue-simulating phantoms and in fully intact lumpectomy …

Abstract Introduction Nationally, 25% to 50% of patients undergoing lumpectomy for local
management of breast cancer require a secondary excision because of the persistence of …

This study aims to determine if light scatter parameters measured with spatial frequency
domain imaging (SFDI) can accurately predict stromal, epithelial, and adipose fractions in …

In breast cancer diagnosis and therapy monitoring, there is a need for frequent, noninvasive
disease progression evaluation. Breast tumors differ from healthy tissue in mechanical …

Spatial frequency-domain imaging (SFDI) utilizes multiple-frequency structured illumination
and model-based computation to generate two-dimensional maps of tissue absorption and …

Spatial frequency domain imaging (SFDI) is a widefield imaging technique that allows for the
quantitative extraction of tissue optical properties. SFDI is currently being explored for small …

Localized measurements of scattering in biological tissue provide sensitivity to
microstructural morphology but have limited utility to wide-field applications, such as surgical …

Near-infrared (NIR) region-based spectroscopy is examined for accuracy with spectral
recovery using frequency domain data at a discrete number of wavelengths, as compared to …

Significance: Spatial frequency domain imaging (SFDI) is a diffuse optical measurement
technique that can quantify tissue optical absorption (μa) and reduced scattering (μ s′) on a …

We have developed a portable, breast margin assessment probe leveraging diffuse optical
spectroscopy to quantify the morphological landscape of breast tumor margins during breast …