Comparison of micron-and nanoparticle deposition patterns in a realistic human nasal cavity

SM Wang, K Inthavong, J Wen, JY Tu… - Respiratory physiology & …, 2009 - Elsevier
Knowledge regarding particle deposition processes in the nasal cavity is important in
aerosol therapy and inhalation toxicology applications. This paper presents a comparative …

Numerical assessment of ambient inhaled micron particle deposition in a human nasal cavity

Y Shang, K Inthavong - Experimental and computational multiphase flow, 2019 - Springer
Understanding the particle exposure characteristics in human respiratory airways plays
important roles in assessing the therapeutic or toxic effects of inhaled particles. In this study …

Airflow and deposition of nano-particles in a human nasal cavity

P Zamankhan, G Ahmadi, Z Wang… - Aerosol science and …, 2006 - Taylor & Francis
A 3D computational model was developed to study the flow and the transport and deposition
of nano-size particle in a realistic human nasal passage. The nasal cavity was constructed …

Numerical analysis of micro-and nano-particle deposition in a realistic human upper airway

PF Ghalati, E Keshavarzian, O Abouali… - Computers in biology …, 2012 - Elsevier
A computational model was developed for studying the flow field and particle deposition in a
human upper airway system, including: nasal cavity, nasopharynx, oropharynx, larynx and …

Laminar airflow and nanoparticle or vapor deposition in a human nasal cavity model

H Shi, C Kleinstreuer, Z Zhang - 2006 - asmedigitalcollection.asme.org
The transport and deposition of nanoparticles, ie, dp= 1–2 nm, or equivalent vapors, in the
human nasal cavities is of interest to engineers, scientists, air-pollution regulators, and …

Detailed micro-particle deposition patterns in the human nasal cavity influenced by the breathing zone

YD Shang, K Inthavong, JY Tu - Computers & Fluids, 2015 - Elsevier
The breathing region connects the nasal cavity with the outside environmental air where
flow is accelerated through the nostrils. Particles introduced into the nasal cavity without …

From the cover: comparative numerical modeling of inhaled nanoparticle deposition in human and rat nasal cavities

J Dong, Y Shang, K Inthavong, J Tu… - Toxicological …, 2016 - academic.oup.com
To gain a better understanding of nanoparticle exposure in human nasal cavities, laboratory
animals (eg rat) are used for in vivo studies. However, due to anatomical differences …

Effect of transient breathing cycle on the deposition of micro and nanoparticles on respiratory walls

K Kuga, R Kizuka, ND Khoa, K Ito - Computer Methods and Programs in …, 2023 - Elsevier
Background and objective From various perspectives (eg inhalation exposure and drug
delivery), it is important to provide insights into the behavior of inhaled particles in the …

Computational fluid dynamics simulations of submicrometer and micrometer particle deposition in the nasal passages of a Sprague-Dawley rat

JD Schroeter, JS Kimbell, B Asgharian… - Journal of aerosol …, 2012 - Elsevier
Computational fluid dynamics (CFD) simulations were conducted in a model of the complete
nasal passages of an adult male Sprague-Dawley rat to predict regional deposition patterns …

Local deposition fractions of ultrafine particles in a human nasal-sinus cavity CFD model

QJ Ge, K Inthavong, JY Tu - Inhalation toxicology, 2012 - Taylor & Francis
Ultrafine particle deposition studies in the human nasal cavity regions often omit the
paranasal sinus regions. Because of the highly diffusive nature of nanoparticles, it is …