Background The optimal method of delivering bronchodilators in mechanically ventilated
patients is unclear. The purpose of this study was to compare the pulmonary bioavailability …

We determined the relative efficacy of two bronchodilator aerosol delivery methods in 18
intubated mechanically ventilated patients with airways obstruction. Two treatment arms …

The delivery of bronchodilators with metered-dose inhaler (MDI) in mechanically ventilated
patients has attracted considerable interest in recent years. This is because the use of the …

Therapeutic aerosols are commonly used in mechanically ventilated patients, mainly to
deliver bronchodilator drugs. Because ventilator-supported patients often receive several …

Metered-dose inhalers (MDIs) provide several advantages over nebulizers, including ease
of administration, decreased cost, reliability of dosing, and freedom from contamination …

OBJECTIVE: Four-hour comparison of the bronchodilator response of albuterol administered
via metered-dose inhaler (MDI) with spacer versus small-volume nebulizer (SVN) to …

Bronchodilators are frequently used in ICU patients, and are the most common medications
administered by inhalation during mechanical ventilation. The amount of bronchodilator that …

Study objective To compare aerosol delivery to the lungs in ventilated patients from two
devices with holding chamber and two devices without holding chamber. Design A …

The optimal dose and technique for administration of bronchodilators with a metered-dose
inhaler (MDI) in mechanically ventilated patients have not been established. We studied the …

We investigated the use of a reservoir device for delivery of a MDI bronchodilator aerosol
using a lung model of an intubated, mechanically ventilated adult. Methods Albuterol …