Muscarinic cholinoceptive neurons in the frontal cortex in Alzheimer's disease

H Schröder, E Giacobini, RG Struble, PGM Luiten… - Brain research …, 1991 - Elsevier
The cellular distribution of muscarinic acetylcholine receptor protein in the frontal cortex of
Alzheimer (AD) patients, age-matched and middle-aged controls was assessed …

Brain nicotinic and muscarinic receptors in normal aging and dementia

A Nordberg, B Winblad - … and Parkinson's Disease: Strategies for Research …, 1986 - Springer
The cholinergic receptors are classically divided into two kinds, namely the nicotinic
acetylcholine receptor and the muscarinic acetyl-choline receptor. The existence of these …

Muscarinic and nicotinic cholinergic binding sites in Alzheimer's disease cerebral cortex

KJ Kellar, PJ Whitehouse, AM Martino-Barrows… - Brain research, 1987 - Elsevier
The total population of muscarinic receptors and a subpopulation of muscarinic receptors
with high affinity for agonists were measured with [3 H] quinuclidinyl benzilate and [3 H] …

Cellular distribution and expression of cortical acetylcholine receptors in aging and Alzheimer's disease.

H Schröder, E Giacobini, RG Struble… - Annals of the New …, 1991 - europepmc.org
Ligand binding studies show marked reductions of nicotinic, but not of muscarinic binding
sites in Alzheimer's disease. Using monoclonal antibodies we studied …

Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease

E Giacobini, RG Struble, K Zilles, A Maelicke - Neurobiology of aging, 1991 - Elsevier
The cellular distribution of nicotinic acetylcholine receptors was studied in the frontal cortex
(area 10) of 1) Alzheimer patients and compared to 2) age-matched and 3) middle-aged …

Cholinergic receptors in cognitive disorders

EK Perry, RH Perry, CJ Smith, D Purohit… - Canadian Journal of …, 1986 - cambridge.org
Cholinergic receptors (muscarinic subtypes M1 and M2, and putative nicotinic binding) have
been examined in the hippocampus obtained at autopsy from a variety of patients with …

Decreased muscarinic receptor binding in cerebral cortex and hippocampus in Alzheimer's disease

KJ Reinikainen, PJ Riekkinen, T Halonen, M Laakso - Life sciences, 1987 - Elsevier
Muscarinic (cholinergic) receptor binding sites (MRB) were studied by determining the 3H-
QNB binding in four cortical areas and hippocampus of 20 histologically confirmed …

Colocalization of muscarinic and nicotinic receptors in cholinoceptive neurons of the suprachiasmatic region in young and aged rats

EA Van der Zee, C Streefland, AD Strosberg, H Schro… - Brain research, 1991 - Elsevier
In the present study muscarinic and nicotinic cholinergic receptors in the SCN region were
demonstrated and analyzed, employing monoclonal antibodies to purified muscarinic and …

Changes in nicotinic and muscarinic cholinergic receptors in Alzheimer‐type dementia

S Shimohama, T Taniguchi, M Fujiwara… - Journal of …, 1986 - Wiley Online Library
Nicotinic and muscarinic cholinergic receptors were studied in autopsied brains from four
histologically normal controls and five histopathologically verified cases of Alzheimer‐type …

Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease

DM Araujo, PA Lapchak, Y Robitaille… - Journal of …, 1988 - Wiley Online Library
The main objective of the present study was to determine whether cholinergic markers
(choline acetyl‐transferase activity and nicotinic and muscarinic receptors) are altered in …