Electrocardiographic imaging of the arrhythmogenic substrate of Brugada syndrome: current evidence and future perspectives

A Galli, A Rizzo, C Monaco, F Salghetti, O Scala… - Trends in cardiovascular …, 2021 - Elsevier
Brugada syndrome is responsible for about 20% of sudden cardiac deaths in patients with
apparently normal hearts. Basic and clinical research has elucidated some of the …

Simultaneous non‐invasive epicardial and endocardial mapping in patients with Brugada syndrome: new insights into arrhythmia mechanisms

B Rudic, M Chaykovskaya, A Tsyganov… - Journal of the …, 2016 - Am Heart Assoc
Background The underlying mechanisms of Brugada syndrome (BrS) are not completely
understood. Recent studies provided evidence that the electrophysiological substrate …

Epicardial Brugada syndrome ablation unmasking inferior J waves

A Lee, H Kohler, D Wright… - Pacing and Clinical …, 2017 - Wiley Online Library
Patients with Brugada syndrome are at risk of life‐threatening ventricular arrhythmias.
Epicardial substrate ablation for Brugada syndrome has been described as a means of …

Right ventricular outflow tract electroanatomical abnormalities in asymptomatic and high‐risk symptomatic patients with Brugada syndrome: Evidence for a new risk …

KP Letsas, K Vlachos, G Conte… - Journal of …, 2021 - Wiley Online Library
Introduction Microstructural abnormalities at the epicardium of the right ventricular outflow
tract (RVOT) may provide the arrhythmia substrate in Brugada syndrome (BrS). Endocardial …

Prevention of ventricular fibrillation episodes in Brugada syndrome by catheter ablation over the anterior right ventricular outflow tract epicardium

K Nademanee, G Veerakul, P Chandanamattha… - Circulation, 2011 - Am Heart Assoc
Background—The underlying electrophysiological mechanism that causes an abnormal
ECG pattern and ventricular tachycardia/ventricular fibrillation (Vt/VF) in patients with the …

Clarifying the Arrhythmogenic Substrate for Brugada Syndrome Electroanatomic Mapping Study of the Right Ventricle

M Kofune, I Watanabe, K Ohkubo, S Ashino… - International Heart …, 2011 - jstage.jst.go.jp
The right ventricular outflow tract (RVOT) is considered the arrhythmogenic region that gives
rise to Brugada syndrome. To obtain a better understanding of this substrate, we performed …

Electrical substrate elimination in 135 consecutive patients with Brugada syndrome

C Pappone, J Brugada, G Vicedomini… - Circulation …, 2017 - Am Heart Assoc
Background—There is emerging evidence that localization and elimination of abnormal
electric activity in the epicardial right ventricular outflow tract may be beneficial in patients …

[HTML][HTML] Repolarization versus depolarization defects in Brugada syndrome: a tale of 2 different electrophysiologic settings?

K Nademanee, AAM Wilde - Clinical Electrophysiology, 2017 - jacc.org
The intense but animated debate between the repolarization versus depolarization
hypotheses as the underlying electrophysiologic mechanism of the Brugada syndrome (BrS) …

[引用][C] Site‐Specific Arrhythmogenesis in Brugada Syndrome?

B Belhassen - Journal of Cardiovascular Electrophysiology, 2003 - Wiley Online Library
The largest studies of patients with Brugada syndrome undergoing electrophysiologic
investigation have mainly addressed the prognostic value of inducible arrhythmias with …

[PDF][PDF] Catheter ablation of Brugada syndrome: importance of repeated administration of ajmaline to unmask the entire epicardial substrate

K Krieger, J Steinfurt, C Lenz… - JACC: Clinical …, 2017 - researchgate.net
A51-year-old man with Brugada syndrome (BrS) was admitted for implantable
cardioverterdefibrillator implantation following outof-hospital cardiac arrest due to ventricular …