This chapter provides a review of recent advances in understanding the importance of
alternative pre-messenger RNA splicing in stem cell biology. The majority of transcribed pre …

Alternative splicing is a crucial regulator in stem cell biology, intricately influencing the
functions of various biological macromolecules, particularly pre-mRNAs and the resultant …

Stem cells have the surprising potential to develop into many different cell types. Therefore,
major research efforts have focused on transplantation of stem cells and/or derived …

Alternative splicing (AS) is an essential mechanism in post-transcriptional regulation and
leads to protein diversity. It has been shown that AS is prevalent in metazoan genomes, and …

Complete information regarding transcriptional and posttranscriptional gene regulation in
stem cells is necessary to understand the regulation of self-renewal and differentiation …

Alternative splicing of messenger RNA (mRNA) precursors affects the majority of human
genes, has a considerable impact on eukaryotic gene function and offers distinct …

The alternative splicing of precursor mRNA is an essential mechanism for protein diversity. It
plays important biological roles, such as proliferation, differentiation and development of …

Development of highly anticipated stem cell-based therapies requires a
detailedunderstanding of mechanisms regulating biological properties of these cells …

The first wave of bioinformatic studies that followed genome and complementary DNA
sequencing projects revealed that alternative splicing of messenger RNA precursors (pre …

Alternative splicing is a process to differentially link exon regions in a single precursor
mRNA to produce two or more different mature mRNAs, a strategy frequently used by higher …