[HTML][HTML] Local and systemic humoral response to autologous lineage-negative cells intrathecal administration in ALS patients
B Baumert, A Sobuś, M Gołąb-Janowska… - International Journal of …, 2020 - mdpi.com
Amyotrophic lateral sclerosis (ALS) remains a fatal disease with limited therapeutic options.
Signaling via neurotrophins (NTs), neuroinflammation, and certain micro-RNAs are believed …
Signaling via neurotrophins (NTs), neuroinflammation, and certain micro-RNAs are believed …
[HTML][HTML] Repeated application of autologous bone marrow-derived lineage-negative stem/progenitor cells—focus on immunological pathways in patients with ALS
B Baumert, A Sobuś, M Gołąb-Janowska… - Cells, 2020 - mdpi.com
Therapeutic interventions in amyotrophic lateral sclerosis (ALS) are still far from satisfying.
Immune modulating procedures raise hopes for slowing the disease progression. Stem cell …
Immune modulating procedures raise hopes for slowing the disease progression. Stem cell …
[HTML][HTML] Safety and feasibility of lin-cells administration to ALS patients: a novel view on humoral factors and miRNA profiles
A Sobuś, B Baumert, Z Litwińska… - International journal of …, 2018 - mdpi.com
Therapeutic options for amyotrophic lateral sclerosis (ALS) are still limited. Great hopes,
however, are placed in growth factors that show neuroprotective abilities (eg, nerve growth …
however, are placed in growth factors that show neuroprotective abilities (eg, nerve growth …
The immunomodulatory effects of human mesenchymal stem cells on peripheral blood mononuclear cells in ALS patients
In a previous study, we reported that intrathecal injection of mesenchymal stem cells (MSCs)
slowed disease progression in G93A mutant superoxide dismutase1 transgenic mice. In this …
slowed disease progression in G93A mutant superoxide dismutase1 transgenic mice. In this …
Intraspinal administration of human spinal cord‐derived neural progenitor cells in the G93A–SOD1 mouse model of ALS delays symptom progression, prolongs …
S Knippenberg, KJ Rath, S Böselt… - Journal of tissue …, 2017 - Wiley Online Library
Neural stem or progenitor cells are considered to be a novel therapeutic strategy for
amyotrophic lateral sclerosis (ALS), based on their potential to generate a protective …
amyotrophic lateral sclerosis (ALS), based on their potential to generate a protective …
[HTML][HTML] Evaluation of the Safety and Efficacy of Repeated Mesenchymal Stem Cell Transplantations in ALS Patients by Investigating Patients' Specific Immunological …
Z Alkhazaali-Ali, S Sahab-Negah, AR Boroumand… - Diseases, 2024 - mdpi.com
Background: Amyotrophic lateral sclerosis (ALS) is an incurable disease. There are vigorous
attempts to develop treatments to reduce the effects of this disease, and among these …
attempts to develop treatments to reduce the effects of this disease, and among these …
[HTML][HTML] Autologous bone marrow-derived stem cells in amyotrophic lateral sclerosis: a pilot study
S Prabhakar, N Marwaha, V Lal, RR Sharma… - Neurology …, 2012 - journals.lww.com
Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with no
effective treatment. Stem cell therapy may be one of the promising treatment options for such …
effective treatment. Stem cell therapy may be one of the promising treatment options for such …
[HTML][HTML] ALS plasma reduces the viability of NSC34 cells via altering mRNA expression of VEGF: A short report
R Khosla, H Bhagat, P Lal, A Anand - Heliyon, 2023 - cell.com
Abstract Introduction Amyotrophic Lateral Sclerosis (ALS) is a devastating
neurodegenerative disorder that progressively leads to motor neuron degeneration at the …
neurodegenerative disorder that progressively leads to motor neuron degeneration at the …
[HTML][HTML] Human umbilical cord blood treatment in a mouse model of ALS: optimization of cell dose
S Garbuzova-Davis, CD Sanberg, N Kuzmin-Nichols… - PLoS …, 2008 - journals.plos.org
Background Amyotrophic Lateral Sclerosis (ALS) is a multicausal disease characterized by
motor neuron degeneration in the spinal cord and brain. Cell therapy may be a promising …
motor neuron degeneration in the spinal cord and brain. Cell therapy may be a promising …
Plasma derived from human umbilical cord blood modulates mitogen-induced proliferation of mononuclear cells isolated from the peripheral blood of ALS patients
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by degeneration of motor neurons in the spinal cord and brain. This disease …
characterized by degeneration of motor neurons in the spinal cord and brain. This disease …