Novel salicylic acid-based chemically crosslinked pH-sensitive hydrogels as potential drug delivery systems

B Demirdirek, KE Uhrich - International Journal of Pharmaceutics, 2017 - Elsevier
In this work, salicylic acid (SA), a non-steroidal anti-inflammatory, was chemically
incorporated into hydrogel systems to achieve sustained SA release profiles. With its anti …

Reinforcement of pH‐responsive γ‐poly (glutamic acid)/chitosan hydrogel for orally administrable colon‐targeted drug delivery

BG Park, HS Kang, W Lee, JS Kim… - Journal of applied …, 2013 - Wiley Online Library
Orally administrable hydrogel was prepared by crosslinking chitosan (CS) with γ‐poly
(glutamic acid)(γ‐PGA) for an excellent pH‐responsive colon‐targeted drug delivery system …

Novel chitosan-based pH-sensitive interpenetrating network microgels for the controlled release of cefadroxil

KSVK Rao, BVK Naidu, MCS Subha, M Sairam… - Carbohydrate …, 2006 - Elsevier
This paper addresses development of novel pH-sensitive interpenetrating polymeric network
(IPN) microgels (MGs) based on chitosan, acrylamide-grafted-poly (vinyl alcohol) and …

Swelling behavior and release properties of pH-sensitive hydrogels based on methacrylic derivatives

T Bartil, M Bounekhel, C Cedric, R Jérôme - Acta pharmaceutica, 2007 - hrcak.srce.hr
Sažetak The purpose of this study is to develop novel intestinal-specific drug delivery
systems with pH sensitive swelling and drug release properties. Methacrylic-type polymeric …

A novel pH-sensitive hydrogel composed of N, O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery

SC Chen, YC Wu, FL Mi, YH Lin, LC Yu… - Journal of controlled …, 2004 - Elsevier
A novel pH-sensitive hydrogel system composed of a water-soluble chitosan derivative (N, O-
carboxymethyl chitosan, NOCC) and alginate blended with genipin was developed for …

A novel pH-sensitive hydrogel based on dual crosslinked alginate/N-α-glutaric acid chitosan for oral delivery of protein

R Gong, C Li, S Zhu, Y Zhang, Y Du, J Jiang - Carbohydrate polymers, 2011 - Elsevier
A novel pH-sensitive hydrogel based on dual crosslinked alginate/N-α-glutaric acid chitosan
(GAC) was prepared. The homogeneous alginate/GAC solution was dropped into calcium …

A drug-loaded gel based on polyelectrolyte complexes of poly (acrylic acid) with poly (vinylpyrrolidone) and chitosan

S Jin, M Liu, S Chen, C Gao - Materials Chemistry and Physics, 2010 - Elsevier
A drug-loaded gel (CSPP) based on ionic crosslinked chitosan (CS) and polyelectrolyte
complexes of poly (acrylic acid)(PAA) with poly (vinylpyrrolidone)(PVP) was prepared by …

Biodegradable pH-responsive polyacrylic acid derivative hydrogels with tunable swelling behavior for oral delivery of insulin

X Gao, C He, C Xiao, X Zhuang, X Chen - Polymer, 2013 - Elsevier
Novel biodegradable and pH-sensitive hydrogels composed of four types of pH-sensitive
polyacrylic acid derivatives (PAAD) and a biodegradable poly (l-glutamic acid)(PGA) …

Injectable multifunctional carboxymethyl chitosan/hyaluronic acid hydrogel for drug delivery systems

F Zhang, S Zhang, R Lin, S Cui, X Jing… - International Journal of …, 2023 - Elsevier
Injectable hydrogels with notable mechanical properties and self-healing ability are
promising carriers for use as a drug delivery system. Here, adipic acid dihydrazide (ADH) …

Designing of pH-sensitive hydrogels for colon targeted drug delivery; characterization and in vitro evaluation

M Suhail, YF Shao, QL Vu, PC Wu - Gels, 2022 - mdpi.com
In the current research work, pH-sensitive hydrogels were prepared via a free radical
polymerization technique for the targeted delivery of 5-aminosalicylic acid to the colon …