Enhanced pH-responsive carrier system based on alginate and chemically modified carboxymethyl chitosan for oral delivery of protein drugs: preparation and in-vitro …

IM El-Sherbiny - Carbohydrate Polymers, 2010 - Elsevier
In this investigation a new series of biodegradable pH-responsive hydrogel microspheres
were prepared, characterized and in-vitro evaluated as potential carriers for oral delivery of …

Design of a pH-responsive oral gel formulation based on the matrix systems of gelatin/hydroxypropyl methylcellulose phthalate for controlled drug release

S Nogami, H Uchiyama, K Kadota, Y Tozuka - International Journal of …, 2021 - Elsevier
Extensive efforts have been directed toward developing novel easily digested formulations
with desirable controlled-release properties. The present study sought to develop pH …

A novel approach for preparation of pH-sensitive hydrogels for enteric drug delivery

L Dong, AS Hoffman - Journal of Controlled Release, 1991 - Elsevier
A new rationale of preparing pH-sensitive hydrogels based on thermally reversible polymers
is proposed, according to which a new class of hydrogels has been synthesized. These …

Synthesis of glutamic acid/polyvinyl alcohol based hydrogels for controlled drug release: In-vitro characterization and in-vivo evaluation

M Suhail, CM Shih, JY Liu, WC Hsieh, YW Lin… - Journal of Drug Delivery …, 2022 - Elsevier
The aim of the current study was to prepare glutamic acid/polyvinyl alcohol based hydrogels
by the free radical polymerization technique. The FTIR analysis of glutamic acid, polyvinyl …

Fabrication of polyethylene glycol hydrogels with enhanced swelling; loading capacity and release kinetics

Q Zahra, MU Minhas, S Khan, PC Wu, M Suhail… - Polymer Bulletin, 2022 - Springer
The objective of current study was to fabricate PEG based hydrogels cross linked with
monomer ie acrylic acid and 2, Acrylamide-2-methyl propane sulfonic acid (AMPS) in …

A pH-sensitive and sustained-release oral drug delivery system: the synthesis, characterization, adsorption and release of the xanthan gum-graft-poly (acrylic acid)/GO …

L Li, X Zheng, C Pan, H Pan, Z Guo, B Liu, Y Liu - RSC advances, 2021 - pubs.rsc.org
In this study, graphene oxide (GO) was successfully prepared using the improved Hummers
method, and the prepared GO powder was dissolved in distilled water and subjected to …

Preparation and characterization of freeze-dried chitosan-poly (ethylene oxide) hydrogels for site-specific antibiotic delivery in the stomach

VR Patel, MM Amiji - Pharmaceutical research, 1996 - Springer
Purpose. The purpose of this study was to develop novel drug delivery systems with pH-
sensitive swelling and drug release properties for localized antibiotic delivery in the …

pH-sensitive hydrogels based on semi-interpenetrating network (semi-IPN) of chitosan and polyvinyl pyrrolidone for clarithromycin release

SS Vaghani, MM Patel - Drug development and industrial …, 2011 - Taylor & Francis
The aim of this study was to develop a pH-sensitive chitosan/polyvinyl pyrrolidone (PVP)
based controlled drug release system for clarithromycin. The hydrogels were synthesized by …

Poly (ethylene glycol)–carboxymethyl chitosan-based pH-responsive hydrogels: photo-induced synthesis, characterization, swelling, and in vitro evaluation as …

IM El-Sherbiny, HDC Smyth - Carbohydrate research, 2010 - Elsevier
In this study, carboxymethyl chitosan was prepared, characterized, and then photo-induced
graft copolymerized with poly (ethylene glycol) under a nitrogen atmosphere in aqueous …

Biodegradable and biocompatible agarose–poly (vinyl alcohol) hydrogel for the in vitro investigation of ibuprofen release

P Date, A Tanwar, P Ladage, KM Kodam, D Ottoor - Chemical Papers, 2020 - Springer
Biodegradable and biocompatible interpenetrating hydrogels consisting of agarose and poly
(vinyl alcohol)(PVA) were synthesized using N, N′-methylene bisacrylamide as the cross …