During acute type B hepatitis, the proportion of inducer to cytotoxic/suppressor T‐cells is
decreased due to an increase in the concentration of suppressor cells. Similar changes are …

Clearance of the hepatitis B virus (HBV), a noncytopathic double-stranded DNA virus,
requires the coordinated response of innate and adaptive, humoral and cellular immune …

To understand the role of cytotoxic T cells in liver damage and viral control, we used human
histocompatibility leukocyte antigen (HLA)-peptide tetramers that allow direct ex vivo …

Hepatocellular injury in hepatitis B virus infection may be produced by an autoaggressive
hepatocytotoxic immune response. To test the hypothesis that acquired suppressor cell …

Peripheral blood T lymphocytes and T-cell subsets were analyzed in 19 patients with HBV-
associated chronic liver disease, in 9 “autoimmune” chronic active hepatitis patients, and in …

The proportions of inducer and cytotoxic/suppressor T cells and their concentrations in
peripheral blood have been determined in patients with acute and chronic type B hepatitis …

Considerable evidence suggests that immune mechanisms are involved in the
pathogenesis of both hepatitis B and C. Both CD4+ and CD8+ T cell responses to viral …

Patients with acute hepatitis B and HBV-induced chronic hepatitis as well as normal control
persons participated in the study. Hepatitis patients of both groups have decreased …

Conclusion In conclusion, until the cellular biology of hepatitis B virus infection is understood
and until the technology for the development of suitable virus infected autologous target …

Cytotoxic T lymphocytes (CTL) and Kupffer cells play an important role in the immune control
of hepatitis B virus (HBV), but may also induce liver injury during infection. We investigated …