Clinical and experimental studies have shown that T cell‐mediated immune mechanisms
are involved in the pathogenesis of hepatitis B virus (HBV) and hepatitis C virus infection …

The composition of the mononuclear cell infiltrate in the liver was studied in patients with
autoimmune and hepatitis B virus (HBV)-induced liver disease. The ratio of inducer to …

Chronic hepatitis B virus (HBV) infection is associated with impairment of HBV‐specific
immune responses. Recently, it has been shown that regulatory T (Treg) cells downregulate …

During infection with hepatitis B or C viruses, cytotoxic T lymphocytes (CTLs) have been
implicated as both the mediators of protection and the principal effectors of liver pathology …

In contrast to convalescent hepatitis B patients, who exhibit the ability to elicit a specific
immune response to HBsAg, patients with chronic hepatitis B virus (HBV) infection are …

The immune response initiated by the T-cell response to viral antigens is thought to be
fundamental for viral clearance and disease pathogenesis in hepatitis B virus (HBV) …

It has been suggested that the cellular immune response to HBV antigens is responsible for
hepatocellular injury in acute and chronic hepatitis B. However, definitive immunological …

T cell proliferative responses to hepatitis B virus-encoded envelope antigen (S+ preS2+
preS1), recombinant core antigen (HBcAg), and natural hepatitis B e antigen (HBeAg) were …

Acute and chronic infection with hepatitis B virus (HBV) is associated with an increased risk
of developing liver disease including cirrhosis, decompensated liver disease, and …

Suppressor cell function was studied in twenty-nine patients with chronic active hepatitis
(CAH) in relation to possible aetiological causes and activity of liver disease. All fifteen …