Differentiating embryonic stem (ES) cells are an increasingly important source of
hematopoietic progenitors, useful for both basic research and clinical applications. Besides …

To explore potentially selective growth conditions for fetal cells in cultures from the blood of
pregnant women, we investigated if fetal and adult erythroid progenitors with different …

Extended studies on mouse embryos during the earliest stages of development are limited
owing to both the large number of preimplantation embryos usually required and the …

Erythropoietin (epo) appears to play a significant role in influencing the proliferation and
differentiation of erythroid progenitor (CFU-E) cells. To determine the mechanism of action of …

OBJECTIVE: To develop a method to produce in culture large number of erythroid cells from
human embryonic stem cells. MATERIALS AND METHODS: Human H1 embryonic stem …

We developed an efficient differentiation induction system (OP9 system) from mouse
embryonic stem (ES) cell to blood cells by coculture on a novel stromal cell line, OP9. This …

Differentiating embryonic stem (ES) cells are increasingly emerging as an important source
of hematopoietic progenitors with a potential to be useful for both basic and clinical research …

The capacity of erythroid-lineage progenitors to form colonies of maturing red blood cells in
semisolid media has provided a functional assay for these progenitors and has greatly …

Background The supply of transfusable red blood cells (RBCs) is not sufficient in many
countries. If erythroid cell lines able to produce transfusable RBCs in vitro were established …

UT-7 is a human megakaryoblastic leukemia cell line with absolute dependence on
interleukin-3, granulocyte-macrophage colony-stimulating factor (GM-CSF), or erythropoietin …