Our objective was to explore the value of additional MR contrasts in elucidating the
decrease in fractional anisotropy (FA) as has been observed in the corticospinal tracts (CST) …

Several quantitative magnetic resonance imaging (MRI) techniques have been proposed to
investigate microstructural tissue changes in amyotrophic lateral sclerosis (ALS) including …

Purpose This paper aims to analyze the contribution of mean diffusivity (MD), axial diffusivity
(AD), and radial diffusivity (RD) in the detection of microstructural abnormalities in …

In this study, we investigated whether diffusion tensor MRI (DTI) could detect progressive
corticospinal tract degeneration in amyotrophic lateral sclerosis (ALS) and whether changes …

Patients with amyotrophic lateral sclerosis (ALS) can present with varying degrees of upper
motor neuron (UMN) and lower motor neuron dysfunction. Previous diffusion tensor imaging …

Objective Using magnetic resonance (MR) high angular resolution diffusion imaging
(HARDI), we aimed at revealing possible microstructural alterations in the early stage of …

Background There is an ongoing debate whether primary lateral sclerosis (PLS) should be
regarded as an independent disease entity separate from amyotrophic lateral sclerosis …

Purpose: To prospectively determine whether diffusion-tensor magnetic resonance (MR)
imaging in conjunction with two-dimensional chemical shift imaging can assist in identifying …

Objective: To assess corticospinal tract involvement in patients with amyotrophic lateral
sclerosis (ALS) by correlating diffusion tensor imaging (DTI) measures with intra-and …

Our aim was to evaluate the location and extent of white matter involvement in patients with
amyotrophic lateral sclerosis (ALS) using diffusion-tensor magnetic resonance imaging …