Two types of melanin pigment are produced in mammals; the brown-to-black eumelanins
and the yellow-to-reddish-brown pheomelanins. The switch from one type of melanin to the …

Melanin and protein synthesis in cultured mouse pigment cells (440W and 440B) were
studied by autoradiography and scintillation counting. The non-pigmented 440W cells did …

The incorporation of natural eumelanin from bovine eyes and synthetic 3, 4-
dihydroxyphenylalanine (dopa) melanin into Chinese hamster ovary (CHO) cells is reported …

Recent investigations and discussions have emphasized not whether tyrosine was a
precursor in melanin formation as had been the controversy for over fifty years (Fitzpatrick …

Co-polymerization of dopa and cysteinyldopa in melanogenesis in vitro Page 1 822 thus
compete with ethanol for binding to the same catalytic site. The increased turnover number in …

The autoxidation of dopa to melanin in culture media causes toxicity to retinal pigment
epithelial (RPE) cells and endothelial cells. The damage is specific to cell type and to the …

The graphical method of Lineweaver-Burk was applied to the histochemical system to obtain
quantitative information on the dopa-oxidase activity in human epidermal melanocytes. In …

In mammals, melanin is synthesized in a specialized secretory cell known as the
melanocyte. This cell is characterized by the presence of tyrosinase, which is responsible for …