Glycosylation in cervical cancer: new insights and clinical implications

Z Xu, Y Zhang, DKW Ocansey, B Wang, F Mao - Frontiers in Oncology, 2021 - frontiersin.org
Cervical cancer has become the most frequent female malignancy and presents as a
general health challenge in many countries undergoing economic development. Various …

Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer

P Martinez-Morales, IM Cruz, L Roa-de la Cruz… - PeerJ, 2021 - peerj.com
Background Dysregulation of glycogene expression in cancer can lead to aberrant glycan
expression, which can promote tumorigenesis. Cervical cancer (CC) displays an increased …

Protein glycosylation as biomarkers in gynecologic cancers

H Shen, CY Lee, CH Chen - Diagnostics, 2022 - mdpi.com
Gynecologic cancers are the leading cause of death in women. Endometrial, ovarian, and
cervical cancer are the three main types of gynecologic cancers. Poor prognoses and high …

Glycosylation in cancer: its application as a biomarker and recent advances of analytical techniques

Y Haga, K Ueda - Glycoconjugate Journal, 2022 - Springer
Despite significant worldwide investment in research, cancer remains one of the most
common cause of death in the world. Early detection and reliable diagnosis are the keys to …

Glycan profiling using formalin‐fixed, paraffin‐embedded tissues: Hippeastrum hybrid lectin is a sensitive biomarker for squamous cell carcinoma of the uterine cervix

A Tozawa‐Ono, M Kubota, C Honma… - Journal of Obstetrics …, 2017 - Wiley Online Library
Aim Glycosylation of proteins is altered in cancer cells and distinctive glycan structures are
associated with specific cancers, but little is known about the complete glycan profile of …

Tumor-associated glycans and their role in gynecological cancers: accelerating translational research by novel high-throughput approaches

T Pochechueva, F Jacob, A Fedier… - Metabolites, 2012 - mdpi.com
Glycans are important partners in many biological processes, including carcinogenesis. The
rapidly developing field of functional glycomics becomes one of the frontiers of biology and …

Glycosylation and its research progress in endometrial cancer

C Pu, Biyuan, K Xu, Y Zhao - Clinical and Translational Oncology, 2022 - Springer
Endometrial cancer (EC) is one of the most common tumors in the female reproductive
system, which seriously threatens women's health, particularly in developed countries. 13 …

Head and neck cancer N-glycome traits are cell line and HPV status–dependent

M Rasheduzzaman, AVM Murugan, X Zhang… - Analytical and …, 2022 - Springer
Glycosylation is the most common post-translational modification of proteins, and
glycosylation changes at cell surfaces are frequently associated with malignant epithelia …

[PDF][PDF] Glycans as a target in the detection of reproductive tract cancers

M Janković, M Kosanović, B Milutinović - Journal of Medical …, 2008 - dmbj.org.rs
The significance of changes in glycosylation for the beginning, progress and outcome of
different human diseases is highly recognized. In this review we summarized literature data …

Functional impact of tumor-specific N-linked glycan changes in breast and ovarian cancers

H Guo, KL Abbott - Advances in cancer research, 2015 - Elsevier
Abstract Changes in glycosylation have been implicated in various human diseases,
including cancer. Research over the past few decades has produced significant findings that …