Loop diuretics are essential in the treatment of patients with heart failure (HF) who develop
congestion. Furosemide is the most commonly used diuretic; however, some randomized …

Background and objective Despite potential advantages of torsemide over furosemide,<
10% of the patients with heart failure (HF) are on torsemide in clinical practice. Prior studies …

Objectives To compare the efficacy and safety of torsemide versus furosemide in patients
with heart failure (HF). Data sources Medline, Cochrane Library, Web of Science, and …

Furosemide has historically been the primary loop diuretic in heart failure patients despite
data suggesting potential advantages with torsemide. We used the Duke Echocardiography …

Although torsemide's oral bioavailability and half-life theoretically render it a more efficient
diuretic than furosemide, the clinical outcomes of torsemide compared with furosemide …

Abraham et al performed a systematic review and meta-analysis of observational studies
and randomized trials comparing torsemide and furosemide for patients with heart failure …

In 2012, total cost for heart failure (HF) was $30.7 billion and by 2030, it is projected to
increase to $69.7 billion [1]. Hospitalizations for HF are a major reason for increased cost …

In this multicenter trial in the United States, investigators randomized patients hospitalized
with acute heart failure (either a new diagnosis or worsening of chronic heart failure) to …

Importance Differences in clinical profiles, outcomes, and diuretic treatment effects may exist
between patients with de novo heart failure (HF) and worsening chronic HF (WHF) …

Aims Loop diuretics have become a mainstay of chronic heart failure management.
Furosemide and torsemide are the two most common loop diuretics; nevertheless, there is …