Myostatin is a highly conserved negative regulator of skeletal muscle growth. Loss of
functional myostatin in cattle, mice, sheep, dogs, and humans results in increased muscle …

Myostatin is a negative regulator of muscle growth. Loss of myostatin has been shown to
cause increase in skeletal muscle size and improve skeletal muscle function and fibrosis in …

Myostatin (MSTN) is a member of the transforming growth factor-β superfamily of cytokines
and is a negative regulator of skeletal muscle mass. Compared with MSTN+/+ mice, the …

Myostatin, a member of the transforming growth factor-β superfamily, has been implicated in
the potent negative regulation of myogenesis in murine models. However, little is known …

Myostatin is a member of the TGF-β family that functions as a negative regulator of skeletal
muscle development and growth in mammals. Recently, Myostatin has also been identified …

Myostatin (Mstn) is a secreted growth factor expressed in skeletal muscle and adipose tissue
that negatively regulates skeletal muscle mass. Mstn−/− mice have a dramatic increase in …

The progressive loss of skeletal muscle mass, strength and/or function with advancing age,
termed sarcopenia, poses a major threat to independence and quality of life. Therefore …

Myostatin inhibits skeletal muscle development. Therefore, we sought to determine whether
larger body and muscle mass in male mice was associated with lower mRNA and protein …

Muscle growth results from a set of complex processes including myogenic transcription
factor's expression and activity, cell cycle withdrawal, myoblast fusion in myotubes, and …

Duchenne muscular dystrophy (DMD) is a lethal, X-linked recessive disease affecting 1 in
3,500 newborn boys for which there is no effective treatment or cure. One novel strategy that …