Myostatin, a member of the transforming growth factor-β (TGF-β) superfamily, is a critical
autocrine/paracrine inhibitor of skeletal muscle growth. Since the first observed double …

Myostatin, which is a member of the TGF-β superfamily, is a negative regulator of skeletal
muscle formation. Double-muscled Piedmontese cattle have a C313Y mutation in myostatin …

Myostatin is a newly described member of the TGF-β superfamily acting as a secreted
negative regulator of skeletal muscle mass in several species, but whose mode of action …

Myostatin, a member of the transforming growth factor-β (TGF-β) superfamily, has been
shown to be a negative regulator of myogenesis. Here we show that myostatin functions by …

Myostatin (Mstn) is a member of the transforming growth factor‐beta family that negatively
regulates skeletal muscle mass. Mstn knockout mice have greater skeletal muscle mass …

Background Myostatin negatively regulates skeletal muscle growth. Myostatin knockout mice
exhibit muscle hypertrophy and decreased interstitial fibrosis. We investigated whether a …

Myostatin is a potent inhibitor of myogenesis; thus differential expression might be expected
across individuals varying in responsiveness to myogenic stimuli. We hypothesized that …