Conserved methylation patterns of human papillomavirus type 16 DNA in asymptomatic infection and cervical neoplasia

M Kalantari, IE Calleja-Macias, D Tewari… - Journal of …, 2004 - Am Soc Microbiol
ABSTRACT DNA methylation contributes to the chromatin conformation that represses
transcription of human papillomavirus type16 (HPV-16), which is prevalent in the etiology of …

[HTML][HTML] The human papillomavirus-18 genome is efficiently targeted by cellular DNA methylation

S Badal, V Badal, IE Calleja-Macias, M Kalantari… - Virology, 2004 - Elsevier
Human papillomaviruses (HPVs) infect epithelia, including the simple and the squamous
epithelia of the cervix, where they can cause cancer and precursor lesions. The molecular …

[HTML][HTML] Distinct human papillomavirus type 16 methylomes in cervical cells at different stages of premalignancy

JL Brandsma, Y Sun, PM Lizardi, DP Tuck, D Zelterman… - Virology, 2009 - Elsevier
Human papillomavirus (HPV) gene expression is dramatically altered during cervical
carcinogenesis. Because dysregulated genes frequently show abnormal patterns of DNA …

CpG methylation of human papillomavirus type 16 DNA in cervical cancer cell lines and in clinical specimens: genomic hypomethylation correlates with carcinogenic …

V Badal, LSH Chuang, EHH Tan, S Badal… - Journal of …, 2003 - Am Soc Microbiol
Infection with genital human papillomaviruses (HPVs) is the primary cause of cervical
cancer. The infection is widespread, and little is known about the secondary factors …

Methylation of the long control region of HPV16 is related to the severity of cervical neoplasia

DC Ding, MH Chiang, HC Lai, CA Hsiung… - European Journal of …, 2009 - Elsevier
OBJECTIVE: Oncogenic human papillomavirus (HPV) is the cause of cervical cancer.
Hypermethylation of the CpG islands located at the long control region (LCR) of the HPV …

[HTML][HTML] Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation

S Vinokurova, M von Knebel Doeberitz - PloS one, 2011 - journals.plos.org
High risk human papillomaviruses are squamous epitheliotropic viruses that may cause
cervical and other cancers. HPV replication depends on squamous epithelial differentiation …

Methylation of viral and host genes and severity of cervical lesions associated with human papillomavirus type 16

K Louvanto, EL Franco… - … journal of cancer, 2015 - Wiley Online Library
Methylation of human papillomavirus (HPV) and host genes may predict cervical cancer risk.
We examined the methylation status of selected sites in HPV16 and human genes in DNA …

[HTML][HTML] Effects of cellular differentiation, chromosomal integration and 5-aza-2′-deoxycytidine treatment on human papillomavirus-16 DNA methylation in cultured …

M Kalantari, D Lee, IE Calleja-Macias, PF Lambert… - Virology, 2008 - Elsevier
Human papillomavirus-16 (HPV-16) genomes in cell culture and in situ are affected by
polymorphic methylation patterns, which can repress the viral transcription. In order to …

[HTML][HTML] Role of DNA methylation in HPV associated lesions

M von Knebel Doeberitz, ES Prigge - Papillomavirus Research, 2019 - Elsevier
Abstractsss Papillomavirus replication is tightly linked to squamous epithelial differentiation
which in turn is governed to a large extent by epigenetic remodeling of genomes within the …

Oncogenic human papillomavirus imposes an instructive pattern of DNA methylation changes which parallel the natural history of cervical HPV infection in young …

SM Leonard, W Wei, SI Collins, M Pereira… - …, 2012 - academic.oup.com
The contribution of early virus-induced epigenetic changes to human papillomavirus (HPV)-
associated carcinogenesis is poorly understood. Using genome-wide methylation array …