Prediction of relapse of acute myeloid leukemia in allogeneic transplant recipients by marrow CD34+ donor cell chimerism analysis

C Scheffold, M Kroeger, M Zuehlsdorf, J Tchinda… - Leukemia, 2004 - nature.com
Chimerism analysis after allogeneic hematopoietic stem cell transplantation (AHSCT)
unveils the conversion of recipient's hematopoiesis to donor type and is useful for detection …

Molecular studies of chimerism and minimal residual disease after allogeneic peripheral blood progenitor cell or bone marrow transplantation.

AH Elmaagacli, DW Beelen, HW Becks… - Bone marrow …, 1996 - europepmc.org
We investigated 23 patients for their chimerism status who underwent allogeneic
transplantation using peripheral blood progenitor cells (PBPCT) for chronic myelogenous …

Frequent detection of minimal residual disease by use of the polymerase chain reaction in long-term survivors after bone marrow transplantation for chronic myeloid …

JM Pignon, T Henni, S Amselem, M Vidaud… - Leukemia, 1990 - europepmc.org
The polymerase chain reaction (PCR) allows the detection of minimal amounts of nucleic
sequences and has been successfully used to test for the chronic myeloid leukemia-specific …

Chimerism analysis within 6 months of allogeneic stem cell transplantation predicts relapse in acute myeloid leukemia

C Huisman, RA De Weger, L De Vries… - Bone marrow …, 2007 - nature.com
The role of chimerism analysis as a prognostic indicator of relapse after hematopoietic stem
cell transplantation (SCT) is controversial. We monitored chimerism status by short tandem …

Clinical significance of bcr-abl gene rearrangement detected by polymerase chain reaction after allogeneic bone marrow transplantation in chronic myelogenous …

R Delage, RJ Soiffer, K Dear, J Ritz - 1991 - ashpublications.org
In chronic myelogenous leukemia (CML), amplification of a segment of bcr-abl messenger
RNA (mRNA) by polymerase chain reaction (PCR) can be used to detect minimal residual …

Molecular analysis of transient cytogenetic relapse after allogeneic bone marrow transplantation for chronic myeloid leukaemia.

F Lin, MA Kirkland, FV Van Rhee, A Chase… - Bone marrow …, 1996 - europepmc.org
Serial quantification of residual disease in CML patients after allogeneic BMT is useful for
early detection of relapse. However, the fact that some cytogenetic relapses appear to be …

Quantitative analysis of chimerism after allogeneic bone marrow transplantation using immunomagnetic selection and fluorescent microsatellite PCR

JP Hancock, NJ Goulden, A Oakhill, CG Steward - Leukemia, 2003 - nature.com
A series of recent publications has highlighted the importance of changing patterns of
donor/recipient chimerism kinetics in the evolution of both relapse and rejection. 1–7 Yet it …

Monitoring of lineage-specific chimaerism allows early prediction of response following donor lymphocyte infusions for relapsed chronic myeloid leukaemia

N Gardiner, M Lawler, JM O'Riordan… - Bone marrow …, 1998 - nature.com
Donor lymphocyte infusions (DLI) have been shown to enhance the graft-versus-leukaemia
(GVL) effect and induce haematological and molecular remission in patients with relapsed …

Predicting Relapse of Chronic Myelogenous Leukemia After Allogeneic Bone Marrow Transplantation by bcr-abl mRNA and DNA Fingerprinting

R Okamoto, H Harano, M Matsuzaki… - American journal of …, 1995 - academic.oup.com
Fourteen patients treated by allogeneic bone marrow transplantation for chronic
myelogenous leukemia (CML) were evaluated by the polymerase chain reaction (PCR) for …

bcr/abl chimeric transcript in patients in remission after marrow transplantation for chronic myeloid leukemia: higher frequency of detection and slower clearance in …

F Frassoni, G Martinelli, G Saglio… - Bone marrow …, 1995 - europepmc.org
The polymerase chain reaction (PCR) was used to amplify the bcr/abl transcript as a marker
of minimal residual disease (MRD) in 76 patients with chronic myeloid leukemia (CML) …