Quantitative chimerism kinetics in relapsed leukemia patients after allogeneic hematopoietic stem cell transplantation

X Qin, GX Li, Y Qin, W Yu, FR Wang, DH Liu… - Chinese Medical …, 2012 - journals.lww.com
Background Chimerism analysis is an important tool for the surveillance of post-transplant
engraftment. It offers the possibility of identifying impending graft rejection and recurrence of …

Characterization of lineage‐specific chimaerism in patients with acute leukaemia and myelodysplastic syndrome after allogeneic stem cell transplantation before and …

P Bader, K Stoll, S Huber, A Geiselhart… - British journal of …, 2000 - Wiley Online Library
Recently, we have shown that patients with acute leukaemias and myelodysplastic
syndromes (MDS), who showed increasing mixed chimaerism (MC) upon serial PCR …

Monitoring of residual disease and guided donor leucocyte infusion after allogeneic bone marrow transplantation by chimaerism analysis with short tandem repeats

RA De Weger, MGJ Tilanus… - British journal of …, 2000 - Wiley Online Library
In this study, we analysed the chimaeric status of peripheral blood leucocytes (PBLs) in
recipients of allogeneic bone marrow transplantation (BMT) with the use of short tandem …

Long-term follow-up of persisting mixed chimerism after partially T cell-depleted allogeneic stem cell transplantation

N Schaap, A Schattenberg, E Mensink, F Preijers… - Leukemia, 2002 - nature.com
Using red cell phenotyping (RCP) and/or cytogenetics (CYT) we identified 19 patients with
persisting mixed chimerism (MC) among 231 patients transplanted with partially T cell …

Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction.

CL Sawyers, L Timson, ES Kawasaki… - Proceedings of the …, 1990 - National Acad Sciences
Relapse of chronic myelogenous leukemia after bone marrow transplantation can be
detected by using clinical, cytogenetic, or molecular tools. A modification of the polymerase …

Minimal residual disease after bone marrow transplant for chronic myeloid leukaemia detected by the polymerase chain reaction

NCP Cross, L Feng, J Bungey… - Leukemia & …, 1993 - Taylor & Francis
We describe the methodology and application of the polymerase chain reaction to detect
BCR-ABL mRNA as a marker for CML cells. The technique is highly sensitive enabling the …

Reliable quantification of hematopoietic chimerism after allogeneic transplantation for acute leukemia using amplification by real-time PCR of null alleles and insertion …

A Jimenez-Velasco, M Barrios, J Roman-Gomez… - Leukemia, 2005 - nature.com
Increasing mixed chimerism (MC) after allogeneic stem cell transplantation (SCT) has been
associated with a high risk of relapse in acute leukemia. We evaluated a new method for …

Quantitative analysis of chimerism after allogeneic stem cell transplantation by real‐time polymerase chain reaction with single nucleotide polymorphisms, standard …

M Koldehoff, NK Steckel, M Hlinka… - American journal of …, 2006 - Wiley Online Library
We compared the results of chimerism analyses with real‐time SNP‐PCR to those obtained
by the classical STR‐PCR method in 135 hematopoietic stem cell transplantation recipients …

[引用][C] Mixed chimerism after bone marrow transplantation and the risk of relapse

E Roux, C Helg, B Chapius, M Jeannet, E Roosnek - 1994 - ashpublications.org
After bone marrow transplantation, recipient hematopoietic cells are usually eradicated by
the combination of the cytotoxic preconditioning regimen and the allogeneic effect of the …

Biological importance of residual leukaemic cells after BMT for CML: does the polymerase chain reaction help?

TP Hughes, JM Goldman - Bone marrow transplantation, 1990 - europepmc.org
The fate of the leukaemic clone after bone marrow transplantation (BMT) for patients with
chronic myeloid leukaemia (CML) may determine the long-term prognosis. Several groups …