With the global increase of the elderly population, the improvement of the treatment for
various aging-related diseases and the extension of a healthy lifespan have become some …

Aging is the primary risk factor for numerous chronic, debilitating diseases. These diseases
impact quality of life of the elderly and consume a large portion of health care costs. The cost …

Model organisms have provided fundamental evidence that aging can be delayed and
longevity extended. These findings gave rise to a new era in aging research aimed at …

Ageing is a process that gradually increases the organism's vulnerability to death. It affects
different biological pathways, and the underlying cellular mechanisms are complex. In view …

There has been, and continues to be, a dramatic shift in the human population towards older
ages necessitating biomedical research aimed at better understanding the basic biology of …

Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

Aging is characterized by an increasing morbidity and functional decline that eventually
results in the death of an organism. Aging is the largest risk factor for numerous human …

Research on longevity and healthy aging promises to increase our lifespan and decrease
the burden of degenerative diseases with important social and economic effects. Many …

The mouse has become the favorite mammalian model. Among the many reasons for this
privileged position of mice is their genetic proximity to humans, the possibilities of …

Human ageing is the gradual decline in organ and tissue function with increasing
chronological time, leading eventually to loss of function and death. To study the processes …