Intermittent vs continuous hypoxia: effects on ventilation and erythropoiesis in humans

N Garcia, SR Hopkins… - … & environmental medicine, 2000 - journals.sagepub.com
Objective Recently, we showed that 5 days of normobaric intermittent hypoxia at rest (IH; 2
hours daily at 3800 m simulated altitude; partial pressure of inspired oxygen 90 torr) can …

Hypoxic preacclimatization combining intermittent hypoxia exposure with physical exercise significantly promotes the tolerance to acute hypoxia

J Xie, S Xie, Z Zhong, H Dong, P Huang… - Frontiers in …, 2024 - frontiersin.org
Background: Both hypoxia exposure and physical exercise before ascending have been
proved to promote high altitude acclimatization, whether the combination of these two …

Effects of intermittent hypoxia on SaO2, cerebral and muscle oxygenation during maximal exercise in athletes with exercise-induced hypoxemia

HC Marshall, MJ Hamlin, J Hellemans… - European journal of …, 2008 - Springer
In a placebo-controlled study, the effects of intermittent hypoxic exposures (IHE) or a
placebo control for 10 days, were examined on the extent of exercise-induced hypoxemia …

A new model of chronic intermittent hypoxia in humans: effect on ventilation, sleep, and blood pressure

R Tamisier, GS Gilmartin, SH Launois… - Journal of applied …, 2009 - journals.physiology.org
Obstructive sleep apnea is characterized by repetitive nocturnal upper airway obstructions
that are associated with sleep disruption and cyclic intermittent hypoxia (CIH) The cyclic …

Long‐term intermittent hyperoxic exposures do not enhance erythropoiesis

ME Keramidas, B Norman, T Gustafsson… - European journal of …, 2012 - Wiley Online Library
Eur J Clin Invest 2012; 42 (3): 260–265 Abstract Background Based on a report of a marked
increase in the erythropoietin concentration ([EPO]) a few hours after the cessation of a …

Combined intermittent hypoxic exposure at rest and continuous hypoxic training can maintain elevated hemoglobin mass after a hypoxic camp

JE Peltonen, A Leppävuori… - Journal of Applied …, 2024 - journals.physiology.org
Athletes use hypoxic living and training to increase hemoglobin mass (Hbmass), but
Hbmass declines rapidly upon return to sea level. We investigated whether intermittent …

Intermittent hypoxic exposure does not improve endurance performance at altitude.

BA Beidleman, SR Muza, CS Fulco… - Medicine and science …, 2009 - europepmc.org
Purpose This study examined the effect of 1 wk of normobaric intermittent hypoxic exposure
(IHE) combined with exercise training on endurance performance at a 4300-m altitude (HA) …

Differential effects of chronic hypoxia and intermittent hypocapnic and eucapnic hypoxia on pulmonary vasoreactivity

JB Snow, V Kitzis, CE Norton… - Journal of applied …, 2008 - journals.physiology.org
Intermittent hypoxia (IH) resulting from sleep apnea can lead to pulmonary hypertension
(PH) and right heart failure, similar to chronic sustained hypoxia (CH). Supplemental CO2 …

Intermittent hypoxia: A call for harmonization in terminology

GS Panza, J Burtscher, F Zhao - Journal of Applied …, 2023 - journals.physiology.org
Mild intermittent hypoxia may be a potent novel strategy to improve cardiovascular function,
motor and cognitive function, and altitude acclimatization. However, there is still a stigma …

Splenic contraction-induced reversible increase in hemoglobin concentration in intermittent hypoxia

I Kuwahira, U Kamiya, T Iwamoto… - Journal of Applied …, 1999 - journals.physiology.org
The effect of intermittent hypoxia (IHx) on blood hemoglobin concentration ([Hb]) and the
underlying mechanisms were studied in rats exposed to 10% O2, 1 h/day, for up to 5 wk. IHx …