Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon
BM Wenk, HA Mbunkah, NN Nsanwe… - Journal of …, 2021 - academic.oup.com
Abstract Objectives In Cameroon, the integrase (IN) strand transfer inhibitor (INSTI)
dolutegravir was recently introduced for the treatment of HIV-1 infection. Since pretreatment …
dolutegravir was recently introduced for the treatment of HIV-1 infection. Since pretreatment …
Baseline integrase drug resistance mutations and conserved regions across HIV-1 clades in Cameroon: implications for transition to dolutegravir in resource-limited …
Background Transition to dolutegravir-based regimens in resource-limited settings (RLS)
requires prior understanding of HIV-1 integrase variants and conserved regions. Therefore …
requires prior understanding of HIV-1 integrase variants and conserved regions. Therefore …
Primary resistance to integrase strand transfer inhibitors in patients infected with diverse HIV-1 subtypes in sub-Saharan Africa
SC Inzaule, RL Hamers… - Journal of …, 2018 - academic.oup.com
Objectives To investigate the prevalence and patterns of major and accessory resistance
mutations associated with integrase strand transfer inhibitors (INSTIs), across diverse HIV-1 …
mutations associated with integrase strand transfer inhibitors (INSTIs), across diverse HIV-1 …
Primary resistance against integrase strand transfer inhibitors in integrase strand transfer inhibitor-naive patients failing first-and second-line ART in Tanzania
S Henerico, E Lyimo, AN Makubi… - Journal of …, 2022 - academic.oup.com
Abstract Introduction Sub-Saharan African countries are introducing integrase strand
transfer inhibitors (INSTIs) in their ART programmes as the preferred first-line regimen, and …
transfer inhibitors (INSTIs) in their ART programmes as the preferred first-line regimen, and …
Drug resistance to integrase strand-transfer inhibitors among HIV-1-infected adults in Guangdong, China
Y Lan, L Li, R Xin, X Ling, X Deng, J Li, L Li, W Cai, F Li… - Pathogens, 2022 - mdpi.com
Background: Integrase strand-transfer inhibitor (INSTI)-containing regimens have gradually
been administered in Guangdong Province, China beginning in 2016, and INSTI-related …
been administered in Guangdong Province, China beginning in 2016, and INSTI-related …
Pre-treatment integrase inhibitor resistance is uncommon in antiretroviral therapy-naive individuals with HIV-1 subtype A1 and D infections in Uganda
SM McCluskey, K Kamelian, N Musinguzi, S Kigozi… - AIDS, 2021 - journals.lww.com
Objective: Dolutegravir (DTG) is now a preferred component of first-line antiretroviral therapy
(ART). However, prevalence data on natural resistance to integrase inhibitors [integrase …
(ART). However, prevalence data on natural resistance to integrase inhibitors [integrase …
Emerging integrase strand transfer inhibitor drug resistance mutations among children and adults on ART in Tanzania: findings from a national representative HIV …
D Kamori, G Barabona, J Rugemalila… - Journal of …, 2023 - academic.oup.com
Background Despite the scale-up of ART and the rollout in Tanzania of dolutegravir, an
integrase strand transfer inhibitor (INSTI), treatment success has not been fully realized. HIV …
integrase strand transfer inhibitor (INSTI), treatment success has not been fully realized. HIV …
Comprehensive Analysis of HIV-1 Integrase Resistance-Related Mutations in African Countries
F Branda, M Giovanetti, L Sernicola, S Farcomeni… - Pathogens, 2024 - mdpi.com
The growing emergence of non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV drug
resistance in sub-Saharan Africa (SSA) led to the World Health Organization (WHO) …
resistance in sub-Saharan Africa (SSA) led to the World Health Organization (WHO) …
Primary resistance to integrase strand-transfer inhibitors in Europe
M Casadellà, PM Van Ham… - Journal of …, 2015 - academic.oup.com
Objectives The objective of this study was to define the natural genotypic variation of the HIV-
1 integrase gene across Europe for epidemiological surveillance of integrase strand-transfer …
1 integrase gene across Europe for epidemiological surveillance of integrase strand-transfer …
Integrase strand transfer inhibitor (INSTI) genotypic resistance analysis in treatment-naive, INSTI free antiretroviral-experienced and INSTI-experienced Turkish …
M Sayan, FS Yildirim, S Akhan, I Karaoglan… - Current HIV …, 2022 - ingentaconnect.com
Background and Objective: Integrase strand transfer inhibitors (INSTIs) are currently the
standard of practice for first-line HIV therapy for most patients. We evaluated the mutations …
standard of practice for first-line HIV therapy for most patients. We evaluated the mutations …