Genetics and epigenetics of eating disorders

Z Yilmaz, JA Hardaway, CM Bulik - Advances in genomics and …, 2015 - Taylor & Francis
Eating disorders (EDs) are serious psychiatric conditions influenced by biological,
psychological, and sociocultural factors. A better understanding of the genetics of these …

Genetic factors in anorexia nervosa

A Kipman, P Gorwood, MC Mouren-Simeoni, J Ades - European psychiatry, 1999 - Elsevier
Anorexia nervosa is a severe and complex disorder with incompletely known vulnerability
factors. It is generally recognized that anorexia nervosa is a familial disorder, but the majority …

Evidence for the role of EP HX2 gene variants in anorexia nervosa

SV Zeeland, CS Bloss, R Tewhey, V Bansal… - Molecular …, 2014 - nature.com
Anorexia nervosa (AN) and related eating disorders are complex, multifactorial
neuropsychiatric conditions with likely rare and common genetic and environmental …

High-throughput DNA methylation analysis in anorexia nervosa confirms TNXB hypermethylation

M Kesselmeier, C Pütter, AL Volckmar… - The World Journal of …, 2018 - Taylor & Francis
Objectives: Patients with anorexia nervosa (AN) are ideally suited to identify differentially
methylated genes in response to starvation. Methods: We examined high-throughput DNA …

The Role of Circadian Rhythms and Sleep in Anorexia Nervosa

H Wilcox, V Paz, R Saxena, JW Winkelman… - JAMA Network …, 2024 - jamanetwork.com
Importance Observational studies have associated anorexia nervosa with circadian rhythms
and sleep traits. However, the direction of causality and the extent of confounding by …

Risk factors for anorexia nervosa: A population‐based investigation of sex differences in polygenic risk and early life exposures

H Chatwin, K Holde, Z Yilmaz, JT Larsen… - … Journal of Eating …, 2023 - Wiley Online Library
Objective To examine sex differences in risk factors for anorexia nervosa (AN). Method This
population‐based study involved 44,743 individuals (6,239 AN cases including 5,818 …

The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa

Z Yilmaz, AS Kaplan, AK Tiwari, RD Levitan… - Journal of psychiatric …, 2014 - Elsevier
Objective Although low weight is a key factor contributing to the high mortality in anorexia
nervosa (AN), it is unclear how AN patients sustain low weight compared with bulimia …

Genetic and environmental influences on anorexia nervosa syndromes in a population–based twin sample

KL Klump, KB Miller, PK Keel, M McGue… - Psychological …, 2001 - cambridge.org
Background. Genetic and environmental influences on broadly-defined anorexia nervosa
(AN) syndrome were examined in a population-based twin sample. Methods. AN syndrome …

Anorexia nervosa trios: behavioral profiles of individuals with anorexia nervosa and their parents

MJ Jacobs, S Roesch, SA Wonderlich… - Psychological …, 2009 - cambridge.org
BackgroundAnorexia nervosa (AN) is associated with behavioral traits that predate the onset
of AN and persist after recovery. We identified patterns of behavioral traits in AN trios …

[HTML][HTML] Gene variants in eating disorders. Focus on anorexia nervosa, bulimia nervosa, and binge-eating disorder

K Donato, MR Ceccarini, K Dhuli, G Bonetti… - Journal of Preventive …, 2022 - ncbi.nlm.nih.gov
Eating disorders such as anorexia nervosa, bulimia nervosa and binge-eating disorder,
have a deep social impact, concluding with death in cases of severe disease. Eating …