… Recent findings with an interesting class of silencing elements, known as Polycomb group
Response Elements (PREs), may shed light on this issue. PREs act as either silencers or …

… The fraction of the human genome covered by ENCODE-detected elements in at least one
… All percentages are calculated against the whole genome, including the portion that is not …

… a fully assembled human genome sequence, large-scale genotyping and gene expression
… detect functional SNPs in TFBSs in the human genome and to predict their impact on the …

… The Encyclopedia of DNA Elements (ENCODE) Project aims to … elements encoded in
the human genome 1–3 . Operationally, we define a functional element as a discrete genome …

… genomic DNA spanning the first exon of the human alpha/beta‐interferon (IFN)‐inducible
gene … These results identify an alpha/beta IFN response element partially homologous to those …

… of EREs (71,119 in the human genome, or about one in every 43 kb of genomic DNA). Not
… We have calculated that the number of EREs found in the human genome in the −1 to + 2-…

… elements, which are often located far away from the genes they control. Our knowledge of
human distal regulatory elements … regulatory sequences throughout the human genome. Here, …

Retroelements constitute a large portion of our genomes. One class of these elements, the
human endogenous retroviruses (HERVs), is comprised of remnants of ancient exogenous …

… We determined the longest segments of the human genome that are maximally conserved …
we call ultraconserved elements (table S1). They are widely distributed in the genome (on all …

… response elements facilitate the exaptation of SINEs to provide a wide variety of regulatory
elements to the human genome, … gene regulation by changing chromatin structure across the …