Review of erlotinib in the treatment of advanced non-small cell lung cancer

KN Ganjoo, H Wakelee - Biologics: Targets and Therapy, 2007 - Taylor & Francis
… This review focuses on erlotinib in advanced stage NSCLC, but the drug is also being
investigated in earlier stages of disease. An ongoing adjuvant trial, RADIANT, is open world-wide …

Erlotinib: a new therapeutic approach for non-small cell lung cancer

P Bonomi - Expert opinion on investigational drugs, 2003 - Taylor & Francis
… In contrast, increasing severity of rash in erlotinib-treated lung cancer patients was … ,
fluorescence in situ hybridisation (FISH) analysis, DNA microarrays or proteomics? In summary, …

Erlotinib in non-small cell lung cancer: a review

FH Blackhall, S Rehman, N Thatcher - Expert opinion on …, 2005 - Taylor & Francis
… paper reviews the pharmacology, preclinical and clinical data to support the use of erlotinib
in … At the time of writing this article a cost–benefit analysis for treatment with erlotinib has not …

[HTML][HTML] Erlotinib in lung cancer—molecular and clinical predictors of outcome

MS Tsao, A Sakurada, JC Cutz, CQ Zhu… - … England Journal of …, 2005 - Mass Medical Soc
… In multivariate analysis, survival after treatment with erlotinib was not influenced by the …
benefit from erlotinib. To clarify the role of EGFR in the outcome of non–small-cell lung cancer, we …

A review of erlotinib and its clinical use

PA Tang, MS Tsao, MJ Moore - Expert opinion on pharmacotherapy, 2006 - Taylor & Francis
… In the Phase I study of erlotinib in combination with carboplatin and paclitaxel, encouraging
activity was observed in patients with non-small cell lung cancer (NSCLC): two patients had …

Erlotinib in the treatment of advanced non-small cell lung cancer: an update for clinicians

Y Wang, G Schmid-Bindert… - Therapeutic advances in …, 2012 - journals.sagepub.com
… This review summarizes the results of recent clinical trials with these tyrosine kinase … of
erlotinib (Table 1). The subgroup analysis showed that the likelihood of a response to erlotinib

[HTML][HTML] Erlotinib in wild type epidermal growth factor receptor non-small cell lung cancer: A systematic review

AR Jazieh, R Al Sudairy, N Abu-Shraie… - Annals of thoracic …, 2013 - journals.lww.com
… This systematic review included Phase III randomized clinical trials that compared single
agent erlotinib to … Random effects meta-analysis was used to pool outcomes across studies. …

Clinical and economic review of erlotinib in non-small-cell lung cancer

K Yeung, JJ Carlson - Expert review of pharmacoeconomics & …, 2012 - Taylor & Francis
… This is an up-to-date review of the clinical and economic impact of erlotinib for advanced
non-small-cell lung cancer. Overall, the studies found that erlotinib, compared with available …

Risk of interstitial lung disease with gefitinib and erlotinib in advanced non-small cell lung cancer: a systematic review and meta-analysis of clinical trials

L Shi, J Tang, L Tong, Z Liu - Lung Cancer, 2014 - Elsevier
… In this analysis, the contribution of gefitinib to the overall … erlotinib. This may be a result of
the larger proportion of patients enrolled in gefitinib trials (61% of all patients in the analysis) …

Erlotinib in the first-line treatment of non-small-cell lung cancer

M D'Arcangelo, F Cappuzzo - Expert review of anticancer therapy, 2013 - Taylor & Francis
… -cell lung cancer (NSCLC) is the leading cause of cancer-… -TKI), such as erlotinib or gefitinib,
demonstrated efficacy in … In this article, the authors analyzed data of erlotinib in NSCLC…