The role of DNA methylation in mammalian epigenetics

PA Jones, D Takai - Science, 2001 - science.org
… afforded by cytosine methylation to provide a heritable mechanism for altering DNA-protein
interactions to assist in such silencing. Genes can be transcribed from methylation-free …

The role of DNA methylation in cancer development.

MW Luczak, PP Jagodziński - Folia histochemica et …, 2006 - journals.viamedica.pl
… Abstract: Epigenetic modifications include DNA methylation … Changes in methylation of
promoter or first exon may mimic … result from aberrations in genomic DNA methylation that include …

Role of DNA methylation in the regulation of transcription

S Eden, H Cedar - Current opinion in genetics & development, 1994 - Elsevier
DNA methylation plays an important role in the regulation of gene expression during
development. Methyl moieties at CpG residues suppress transcription by affecting DNA-protein …

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… improved our knowledge of DNA methylation dynamics and … DNA methylation in embryonic,
germline and somatic cell development. Finally, we provide insights into DNA methylation

DNA methylation

R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… aspects of DNA methylation and its role in transcription repression, neoplasia, and transgene
silencing and during development. In the interest of brevity, the role of DNA methylation in …

The role of DNA methylation in cancer

R Lakshminarasimhan, G Liang - DNA Methyltransferases-Role and …, 2016 - Springer
… of DNA methylation is a critical epigenetic mechanism of cancer initiation, maintenance, and
progression. Proper control of DNA methylation … the aberrant DNA methylation changes that …

The role of DNA methylation in cancer

PA Jones, JD Buckley - Advances in cancer research, 1990 - Elsevier
… are consistent with DNA methylation playing a role in marking the paternal and maternal
gene sets during early development. However, definitive proof that methylation is involved in …

Role for DNA methylation in genomic imprinting

E Li, C Beard, R Jaenisch - Nature, 1993 - nature.com
DNA methylation plays a critical role in genomic imprinting. Specifically, DNA methylation is
… Our data do not address, however, whether DNA methylation plays a functional role in estab…

Dynamics and context-dependent roles of DNA methylation

C Ambrosi, M Manzo, T Baubec - Journal of molecular biology, 2017 - Elsevier
… focuses on general features of DNA methylation and how this modification is regulated
and discusses the dynamics of genome-wide DNA methylation patterns in murine embryonic …

The role of DNA methylation in ageing and cancer

AE Morgan, TJ Davies, MT Mc Auley - Proceedings of the Nutrition …, 2018 - cambridge.org
DNA methylation, and its association with cancer and ageing. The review will outline the key
factors, including diet, which modulate DNA methylation… by aberrant DNA methylation, a key …