… CONCLUSIONS The role of DNA methylation as a locking mechanism for gene
expression in somatic cells is well established, but much remains to be done to improve our …

… The role of this interesting enzyme with respect to maintenance of DNA methylation patterns
and … Although these aspects of DNA methylation are very interesting, they are not discussed …

… role in establishing cellular identities and controlling gene expression. Herein, we summarize
the current knowledge about the role of epigenetics, and specifically DNA methylation …

… This study examined the role of Apaf-1 methylation in leukaemia using polymerase chain
reaction (PCR)-based technique to determine the potential role in leukaemiagenesis. The cell …

… has captured a lot of interest and its fundamental role in proper cell functioning is broadly
recognized. Numerous studies have shown the key role of DNA methylation in tumor …

… Several studies demonstrated the role of dietary micronutrients during early life in altering …
mechanisms such as DNA methylation [20]. The alteration in the methylation patterns of CpGs …

… To arrive at this explanatory framework, we begin by discussing the functional roles of DNA
methylation at the cellular and organismic levels. We then discuss studies that exemplify how …

… for changes in folate intake to modulate DNA methylation both as a biomarker for … role of
DNA methylation in normal genome function, how it can be altered, and the evidence of the role …

… Methylation of DNA at position five of the cytosine ring occurs … of the mechanisms by which
DNA methylation is targeted to … Recent studies have illuminated the role of DNA methylation …

… and function of DNA methylation. Restriction enzymes made it possible to study the state of
methylation of specific sites, rather than the degree of gross methylation of the DNA (22). Our …