Safety evaluation of ocular drug delivery formulations: techniques and practical considerations
BG Short - Toxicologic pathology, 2008 - journals.sagepub.com
… formulations and permeability enhancers. Intravitreal, subconjunctival, and periocular routes
of administration and sustained-release formulations of … implants to deliver drugs to the …
of administration and sustained-release formulations of … implants to deliver drugs to the …
Drug safety assessment of oral formulations of ketoconazole
… Areas covered: This drug safety review summarizes reports of oral ketoconazole-related
adverse events retrieved from a search of the PubMed database using the search strategy ‘…
adverse events retrieved from a search of the PubMed database using the search strategy ‘…
Advances in nutraceutical delivery systems: From formulation design for bioavailability enhancement to efficacy and safety evaluation
RFS Gonçalves, JT Martins, CMM Duarte… - Trends in Food Science …, 2018 - Elsevier
… drug delivery system (SEDDS) composed of Capmul MCM as the oil phase, Tween 20 as
surfactant and ethanol as co-surfactant and its stability and antioxidant capacity was evaluated. …
surfactant and ethanol as co-surfactant and its stability and antioxidant capacity was evaluated. …
[图书][B] Drug safety evaluation
SC Gad - 2016 - books.google.com
… Most of what will be presented and discussed in this volume speaks to regulatory
requirements for nonclinical safety assessment in the general case for either small molecules or …
requirements for nonclinical safety assessment in the general case for either small molecules or …
Drug delivery and formulations
J Breitkreutz, J Boos - Pediatric Clinical Pharmacology, 2011 - Springer
… Drug delivery to children is still a major challenge. Key issues are age-appropriate formulations,
safety of excipients, suitability of drug delivery devices and therapy compliance. Some …
safety of excipients, suitability of drug delivery devices and therapy compliance. Some …
Nanomedicines for ocular NSAIDs: safety on drug delivery
… drugs are used in eye surgery. In this review we focus on microemulsions, polymeric
nanoparticles, liposomes, solid lipid nanoparticles, and drug nanocrystals as formulations …
nanoparticles, liposomes, solid lipid nanoparticles, and drug nanocrystals as formulations …
Safety of nanosuspensions in drug delivery
L Wang, J Du, Y Zhou, Y Wang - … : Nanotechnology, Biology and Medicine, 2017 - Elsevier
… properties, stabilizing the formulation is an important factor influencing drug delivery safety.
Stabilizer selection is a large challenge during pharmaceutical product development that …
Stabilizer selection is a large challenge during pharmaceutical product development that …
Safety assessment of nanoparticles for drug delivery by means of classic in vitro assays and beyond
S Lorscheidt, A Lamprecht - Expert opinion on drug delivery, 2016 - Taylor & Francis
… , for modifying tissue distribution of antitumor drugs and reducing toxic side … Drug Administration
(FDA) approved the first nanocarrier-based drug, a liposomal doxorubicin formulation, …
(FDA) approved the first nanocarrier-based drug, a liposomal doxorubicin formulation, …
Drug delivery approaches in addressing clinical pharmacology-related issues: opportunities and challenges
H Wen, H Jung, X Li - The AAPS journal, 2015 - Springer
… ten drugs using sterile long-acting release (LAR) formulations … , drug delivery systems have
been used in delaying drug … type of formulation design more risky from safety perspective. …
been used in delaying drug … type of formulation design more risky from safety perspective. …
Recent advances in green nanoparticulate systems for drug delivery: efficient delivery and safety concern
… This review highlights the potential risks of nanomedicine formulations to health, delivery
routes of … Nanoscale formulation has been used for drug delivery over the last decade. This …
routes of … Nanoscale formulation has been used for drug delivery over the last decade. This …
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