Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis

A Kanashiro, F Sônego, RG Ferreira… - Pharmacological …, 2017 - Elsevier
… induce the release of pro-inflammatory mediators (cytokines, chemokines… systemic bacterial
dissemination. However, during the sepsis, the presence of excessive systemic inflammation

Current trends in inflammatory and immunomodulatory mediators in sepsis

M Aziz, A Jacob, WL Yang, A Matsuda… - Journal of leukocyte …, 2013 - academic.oup.com
Sepsis refers to severe systemic inflammation in response to … treatment in sepsis animals
reduced systemic inflammation and … striking features of reducing systemic inflammation, as well …

Is neuroimmunomodulation a future therapeutic approach for sepsis?

V Kumar, A Sharma - International immunopharmacology, 2010 - Elsevier
systemic inflammation responsible for sepsis development. However, treatment of patients
suffering from sepsis or its more severe form (ie severe sepsis or septic … of sepsis causing high …

Integral estimation of systemic inflammatory response under sepsis

NV Zotova, YA Zhuravleva, TE Zubova, EY Gusev - 2020 - elar.urfu.ru
systemic inflammatory response (SIR), specific to the development of critical states in sepsis,
… 167 patients with a diagnosis of sepsis (43 patients with sepsis according to definitions of “…

[HTML][HTML] The impact of the systemic inflammatory response on hepatic bacterial elimination in experimental abdominal sepsis

K Hanslin, J Sjölin, P Skorup, F Wilske… - Intensive Care Medicine …, 2019 - Springer
… The mechanisms underlying decreased bacterial elimination by the liver in systemic
inflammation seen in our study are unclear. Several mechanisms in the liver are affected by sepsis […

[PDF][PDF] Systemic inflammatory response syndrome: septic shock

D Purvis, R Kirby - Veterinary Clinics of North America-Small Animal …, 1994 - academia.edu
… that cause systemiC inflammatory changes. The … of inflammatory mediators is called the
systemic inflammatory response syndrome (SIRS). Inciting diseases include sepsis and septic

[HTML][HTML] Sepsis: a review of advances in management

J Rello, F Valenzuela-Sánchez, M Ruiz-Rodriguez… - … in therapy, 2017 - Springer
… The Sepsis-3 definitions call for a new clinical tool to replace the criteria for systemic
inflammatory response syndrome (SIRS) in identifying patients with sepsis. These criteria are non-…

Granulocyte colony-stimulating factor to prevent the progression of systemic nonresponsiveness in systemic inflammatory response syndrome and sepsis

M Weiss, LL Moldawer… - Blood, The Journal of the …, 1999 - ashpublications.org
… of the inflammatory circuits during SIRS and sepsis are summarized. Exogenous G-CSF (dashed
lines) can interrupt a fulminant proinflammatory and anti-inflammatory response by …

Immunotherapy of sepsis

T Van Der Poll - The Lancet infectious diseases, 2001 - thelancet.com
… Figure 1Proinflammatory and anti-inflammatory events during sepsis. Sepsis likely is
associated with an early phase of excessive systemic inflammation mediated by various …

[HTML][HTML] Sepsis and septic shock

RS Hotchkiss, LL Moldawer, SM Opal… - Nature reviews Disease …, 2016 - nature.com
Sepsis has been … , sepsis and its treatment have confounded investigators for nearly 3,000
years. Since 1991, the consensus definition of sepsis has been the ‘systemic inflammatory