Management of severe sepsis and septic shock: challenges and recommendations

A Gullo, N Bianco, G Berlot - Critical care clinics, 2006 - criticalcare.theclinics.com
… genetic predisposition to sepsis and septic shock in some individuals [3]. Sepsis still
remains one of the main problems in medicine and a continuous challenge for intensive care …

Management of severe sepsis: advances, challenges, and current status

I Martin-Loeches, MM Levy, A Artigas - Drug design, development …, 2015 - Taylor & Francis
… into consideration the absence of significant clinical benefit and the potential harmful effect
of starches based on the above studies, the 2013 SSC Citation28 guidelines recommended

[PDF][PDF] Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future

MJ Schultz, MW Dünser, AM Dondorp… - Sepsis management …, 2019 - library.oapen.org
… Whereas the majority of severe sepsis in HICs is caused by bacterial infections, in LMICs, …
is that fluid bolus resuscitation is not recommended in hyperlactatemic patients with severe falci…

[HTML][HTML] Challenges and solutions in translating sepsis guidelines into practice in resource-limited settings

S Ranjit, N Kissoon - Translational Pediatrics, 2021 - ncbi.nlm.nih.gov
challenges in defining sepsis in LMIC, extrapolation of international treatment recommendations
in LMIC is fraught with challenges… for patients with severe sepsis in resource-limited …

Diagnostic challenges in sepsis

CF Duncan, T Youngstein, MD Kirrane… - Current Infectious …, 2021 - Springer
… surviving sepsis campaign guidelines recommends hospitals implement a sepsis screening
… not yield positive results even in the presence of severe sepsis (a now redundant term) [72, …

Fluid resuscitation in severe sepsis and septic shock: an evidence-based review

JL Vincent, H Gerlach - Critical care medicine, 2004 - journals.lww.com
… the literature graded along five levels to create recommendation grades from A to E, with A
… of severe sepsis may consist of natural or artificial colloids or crystalloids. Fluid challenge

… Diseases Society of America position paper: recommended revisions to the national severe sepsis and septic shock early management bundle (SEP-1) sepsis quality …

C Rhee, K Chiotos, SE Cosgrove… - Clinical Infectious …, 2021 - academic.oup.com
Sepsis is even more complicated and challenging than pneumonia, however, because it
includes a heterogeneous mix of infections and organ dysfunctions, all of which have many …

Pregnancy-associated severe sepsis: contemporary state and future challenges

L Oud - Infectious Diseases and Therapy, 2014 - Springer
… A lung-protective strategy has been recommended in patients with acute respiratory distress
syndrome [17]. This approach involves among other components use of lower tidal volume …

Challenges with diagnosing and managing sepsis in older adults

KM Clifford, EA Dy-Boarman, KK Haase… - Expert review of anti …, 2016 - Taylor & Francis
… and offers recommendations for monitoring and treating sepsis in the older adult population.
… Many clinical trials of adult patients with severe sepsis and septic shock include a large …

[HTML][HTML] More challenges around sepsis: definitions and diagnosis

E Joynes - Journal of thoracic disease, 2016 - ncbi.nlm.nih.gov
Severe sepsis is sepsis with organ dysfunction and septic shock is sepsis with persistent …
as a life threatening condition and has removed severe sepsis from the definition. Both …