Early management of severe sepsis: concepts and controversies

PE Marik - Chest, 2014 - Elsevier
severe sepsis in 2009, which would place severe sepsis as … severe sepsis and septic shock
may be as high as 44%. In addition, some data suggest that patients who have had a septic

New sepsis and septic shock definitions: clinical implications and controversies

C Rhee, M Klompas - Infectious Disease Clinics, 2017 - id.theclinics.com
… rate, and white blood cell count, with severe sepsis referring to sepsis with organ dysfunction
and septic shock referring to sepsis with refractory hypotension. This construct remained in …

[HTML][HTML] What is sepsis? What is severe sepsis? What is septic shock? Searching for objective definitions among the winds of doctrines and wild theories

DF Gaieski, M Goyal - Expert review of anti-infective therapy, 2013 - Taylor & Francis
sepsis, 18% severe sepsis and 4% septic shock. They noted a stepwise increase in mortality
as patients moved along the SIRS–sepsissevere sepsissepticsevere sepsis and septic

Early goal-directed therapy in severe sepsis and septic shock revisited: concepts, controversies, and contemporary findings

RM Otero, HB Nguyen, DT Huang, DF Gaieski, M Goyal… - Chest, 2006 - Elsevier
… Although hypotension is currently used to define the transition from severe sepsis to septic
… early sepsis. The employment of lactate levels of ≥ 4 mmol/L as a marker for severe tissue …

Rethinking the concept of sepsis and septic shock

JA Cabrita, I Pinheiro, LM Falcão - European Journal of Internal Medicine, 2018 - Elsevier
… In this document, severe sepsis indicated the presence of organ failure, and septic shock
was defined by the presence of acute circulatory failure and arterial hypotension (Table 1) [5, 6]…

[HTML][HTML] Sepsis: evolving concepts and challenges

R Salomão, BL Ferreira, MC Salomão… - Brazilian Journal of …, 2019 - SciELO Brasil
concepts of sepsis, from the “systemic inflammatory response syndrome triggered by infection”
(Sepsis-1) to “a severe… of immunomodulatory therapies in severe sepsis and septic shock. …

Current concepts in severe sepsis and septic shock

MI Rudis, KL Rowland - Journal of pharmacy practice, 2005 - journals.sagepub.com
severe sepsis or septic shock with APACHE II scores >25 to help mitigate the prothrombotic
effects of severe sepsis … , DAA administration to patients with severe sepsis and septic shock …

New concepts in sepsis

CN Sessler, W Shepherd - Current Opinion in Critical Care, 2002 - journals.lww.com
… Each successive year of clinical and basic investigation into severe sepsis and septic shock
… A recent study predicts nearly 1 million episodes of severe sepsis annually in the United …

[HTML][HTML] Controversies regarding the new definition of sepsis

JH Jeon, DW Park - The Korean Journal of Medicine, 2017 - ekjm.org
… inflammatory response syndrome or the concept of ‘severe sepsis.’ The SEPSIS-3 definition
aims to devise more precise descriptions of sepsis and to improve clinical care. However, …

Controversies of surviving sepsis campaign bundles: should we use them?

FR Machado, FGR Freitas - Shock, 2008 - journals.lww.com
… The same applies to the results of the Volume Substitution and Insulin Therapy in Severe
Sepsis trial, designed to evaluate not only the effects of hyperglycemia but also two types of …