New therapeutic approaches in sepsis: a critical review

LA Eidelman, R Pizov, CL Sprung - Intensive Care Medicine, 1995 - Springer
… al of IL-I ra in patients with severe sepsistherapeutic modalities in sepsis, we have not
observed these results in the recent human trials. Why have new effective therapies for sepsis not …

Anti-inflammatory therapies in sepsis and septic shock

BD Freeman, C Natanson - Expert opinion on investigational drugs, 2000 - Taylor & Francis
… not only regarding this therapeutic approach, but the role of inflammation in sepsis. In this …
collapse, indistinguishable from that occurring in severe sepsis [8]. Later animal studies …

Appraisal of four novel approaches to the prevention and treatment of sepsis

A Kumar, HJ Mann - American journal of health-system …, 2004 - academic.oup.com
… of four novel therapeutic approaches—drotrecogin … approaches to sepsis discussed in
this article varies across the cascade from SIRS through sepsis through severe sepsis to septic

The end of “one size fits all” sepsis therapies: toward an individualized approach

JL Vincent, T van der Poll, JC Marshall - Biomedicines, 2022 - mdpi.com
… The administration of hydrocortisone to patients with severe septic shock was associated …
We need to redefine critical illness to align disease taxonomy with therapeutic approaches [101]…

[PDF][PDF] Sepsis: Menu of new approaches replaces one therapy for all

SP Larosa - Cleveland Clinic journal of medicine, 2002 - cdn.mdedge.com
severe sepsis and steroid replacement therapy in refractory septic shock with adrenal
hyporesponsiveness represents not the end of severe sepsis research and therapysevere sepsis

Sepsis-induced AKI: From pathogenesis to therapeutic approaches

FF He, YM Wang, YY Chen, W Huang, ZQ Li… - Frontiers in …, 2022 - frontiersin.org
severe acute pancreatitis, serious trauma and so on. According to the degree of severity, it
can be classified as sepsis, severe sepsis… a new therapeutic approach for sepsis-induced AKI. …

Severe sepsis and septic shock: review of the literature and emergency department management guidelines

HB Nguyen, EP Rivers, FM Abrahamian… - Annals of emergency …, 2006 - Elsevier
… and therapeutic advances in severe sepsis and septic shock … Recommendations are provided
for therapies that have been … new approaches to management of severe sepsis and septic

Novel pharmacologic approaches to the management of sepsis: targeting the host inflammatory response

DS Wheeler, B Zingarelli, WJ Wheeler… - Recent patents on …, 2009 - ingentaconnect.com
… protein C in 1,690 critically ill adults with severe sepsis was able to demonstrate an absolute
… both the safety and efficacy of this therapeutic approach in critically ill patients with severe

Sepsis therapies: learning from 30 years of failure of translational research to propose new leads

JM Cavaillon, M Singer, T Skirecki - EMBO molecular medicine, 2020 - embopress.org
… term consequences of surviving sepsis and, finally, list some putative approaches—both old
… a human disease or at proposing new therapeutic approaches to improve health outcome. …

Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock

, … Sepsis Campaign Management Guidelines … - Critical care …, 2004 - journals.lww.com
… is less well suited to this approach. Readers will note that the … therapy for neutropenic
patients with severe sepsis or septic shock. For neutropenic patients, broad-spectrum therapy