[HTML][HTML] Key signaling pathways in thyroid cancer
MA Zaballos, P Santisteban - Journal of Endocrinology, 2017 - joe.bioscientifica.com
… signaling pathways and driver oncogenes related to thyroid tumorigenesis, focusing on the
MAPK and PI3K pathways, whose relevance as drivers of oncogenesis in the thyroid gland …
MAPK and PI3K pathways, whose relevance as drivers of oncogenesis in the thyroid gland …
[HTML][HTML] Thyroid carcinoma: molecular pathways and therapeutic targets
YE Nikiforov - Modern Pathology, 2008 - Elsevier
… MAPK signaling pathway is physiologically activated by binding of growth factors to receptor
tyrosine kinases (RTKs), such as RET and NTRK, resulting in receptor dimerization and …
tyrosine kinases (RTKs), such as RET and NTRK, resulting in receptor dimerization and …
[HTML][HTML] Signaling pathways in thyroid cancer and their therapeutic implications
S Jin, O Borkhuu, W Bao, YT Yang - Journal of clinical medicine …, 2016 - ncbi.nlm.nih.gov
… in these signaling pathways and targeted treatments of thyroid cancer were … pathways. In
the present work, the advances in these signaling pathways and targeted treatments of thyroid …
the present work, the advances in these signaling pathways and targeted treatments of thyroid …
TSH-activated signaling pathways in thyroid tumorigenesis
M Rivas, P Santisteban - Molecular and cellular endocrinology, 2003 - Elsevier
… implicated in thyroid pathology. In this review we focus on the different signaling
pathways involved in TSH-mediated proliferation and their role in thyroid transformation and …
pathways involved in TSH-mediated proliferation and their role in thyroid transformation and …
Cellular signaling pathway alterations and potential targeted therapies for medullary thyroid carcinoma
S Giunti, A Antonelli, A Amorosi… - International journal of …, 2013 - Wiley Online Library
… However, this paper will mainly focus on additional cellular signaling pathways other than
RET responsible of MTC tumorigenesis and progression and potential targeted approaches …
RET responsible of MTC tumorigenesis and progression and potential targeted approaches …
An update on molecular biology of thyroid cancers
O Omur, Y Baran - Critical reviews in oncology/hematology, 2014 - Elsevier
… signaling pathways; microRNA profiles and aberrant methylation have been demonstrated
in more than 70% of DTC. Diagnostic use of these molecular markers may be optimized for …
in more than 70% of DTC. Diagnostic use of these molecular markers may be optimized for …
[HTML][HTML] Signaling pathways in follicular cell-derived thyroid carcinomas
M Romitti, L Ceolin, DR Siqueira… - International …, 2013 - spandidos-publications.com
… carcinomas may … signaling pathways. These distinct genetic alterations constitutively
activate the MAPK, PI3K and β-catenin signaling pathways, which have been implicated in thyroid …
activate the MAPK, PI3K and β-catenin signaling pathways, which have been implicated in thyroid …
Multiple signaling pathways converge on β-catenin in thyroid cancer
… In this review, we put forth the hypothesis that multiple signaling pathways can ultimately
result in -catenin activation in dedifferentiated thyroid cancer. However, whether these pathways…
result in -catenin activation in dedifferentiated thyroid cancer. However, whether these pathways…
PI3K/AKT pathway and its mediators in thyroid carcinomas
Z Nozhat, M Hedayati - Molecular diagnosis & therapy, 2016 - Springer
… in a broad number of cancers, including thyroid carcinomas. In this review article, the role
of different signaling pathways of PI3K/AKT in thyroid cancers, with the emphasis on the PI3K/…
of different signaling pathways of PI3K/AKT in thyroid cancers, with the emphasis on the PI3K/…
… of BRAF Mutations in Thyroid Cancer: Genetic Evidence for Constitutive Activation of the RET/PTC-RAS-BRAF Signaling Pathway in Papillary Thyroid Carcinoma
… Because these signaling proteins function along the same pathway in thyroid cells, this
represents a unique paradigm of human tumorigenesis through mutation of three signaling …
represents a unique paradigm of human tumorigenesis through mutation of three signaling …
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