… waking activity in Clk Jrk , Clk ar , and cyc 0 mutants and found that all mutants tested have
waking … neurons (LNvs) that express the neuropeptide Pigment dispersing factor (Pdf). Clk is …

… As sleep pressure builds during waking, the sleep-promoting … downstream of sleep-control
neurons in Drosophila. We find … transmitters that include the neuropeptide allatostatin-A (AstA)…

… It is therefore predicted to promote wakefulness … wake-promoting clock neurons promotes
sleep, revealing a previously unappreciated complexity in the dopaminergic control of sleep. …

… transmission, are involved in sleep is not clear. Here, we show that Drosophila Nlg4 (DNlg4) …
Therefore, sleep circuits downstream of l-LNvs and unknown wake-promoting neurons may …

… Similarly, in Drosophila, synaptic morphology at the … whether sleep and wake affect synaptic
density and size. … of the wake promoting system (19) and express the neuropeptide pigment …

… within which GABAergic sleep-promoting neurons oppose arousal. Drosophila sleep has
recently … behavior of pdf01 mutant flies, which lack this neuropeptide transmitter. Compared to …

… of Drosophila neurons and circuits affecting vigilance, sleep, … for other behavioral and sleep
studies in Drosophila (36). … and phase resetting ensure that sleep–wake patterns and the …

… of the neurophysiological patterns of specific sleep/wake circuits in Drosophila, which is …
that mediate homeostatic and circadian regulation of sleep in Drosophila. Based on work in the …

… We assessed sleep-wake modulation by a core set of circadian pacemaker neurons that
express the neuropeptide PDF. We find that disruption of PDF function increases …

… In Drosophila melanogaster, large ventral lateral neurons (l-… to promote wakefulness through
the action of the neuropeptide … of sleep and wake states, thereby modulating sleep/wake …