… Improvement in dissolution rate by increasing the surface area through particle size reduction
of poorly soluble drugs results in poor bioavailability 1 . Poorly soluble drug creates the …

… Nanogels have greater potential as novel, safe, and effective carrier system for solubility
enhancement of poor soluble drugs due to smaller size, large surface area, high drug loading …

… This process is known as micellisation and generally results in enhanced solubility of
poorly soluble drugs. Commonly used non-ionic surfactants include polysorbates, polyoxy …

… a sparingly water- soluble drug and a highly water- soluble carrier … increased rate of dissolution
of a poorly water- soluble drug. … in dissolution rates of the sparingly water-soluble drugs …

… used for the improvement of the solubility of poorly water soluble drugs include
hydrotrophy, use of salt form, use of precipitation inhibitors, alteration of pH of the drug micro-environment…

… by increasing the solubility of these drugs. This review article … enhancing the solubility of
poorly water-soluble drugs. KEYWORDS: Solubility, BCS class II drugs, solubility enhancement, …

… for solubility enhancement of hydrophobic drugs for oral pharmaceutical formulation. … for
enhancing drug solubility to reduce the percentage of poorly soluble drug candidates eliminated …

… The solubility behavior remains one of the most challenging … for the improvement of solubility
of poorly water soluble drugs which … means of improving the dissolution rate and hence the …

… of a slightly soluble drug and an inert, highly water soluble carrier, is dissolved in an aqueous
medium, the carrier will dissolve rapidly, releasing very fine crystals of the drug. The large …

… Development of Supersaturable self emulsifying drug delivery system formulations for
improving the oral absorption of poorly soluble drugs. Expert Opin. Drug Del., 2006, 3: 97-110. [39] …