Thermodynamic analysis and molecular dynamic simulation of solid–liquid equilibrium behavior of antipsychotic drug aripiprazole (Form III) in three binary solvent …
H Wang, X Zhang - Journal of Molecular Liquids, 2023 - Elsevier
… negative, indicating that the dissolution process of APZ Form III … method for the separation
and preparation of crystals with specific structures. For the crystallization process, the solubility …
and preparation of crystals with specific structures. For the crystallization process, the solubility …
Tuning physicochemical properties of antipsychotic drug aripiprazole with multicomponent crystal strategy based on structure and property relationship
Y Zhao, B Sun, L Jia, Y Wang, M Wang… - Crystal Growth & …, 2020 - ACS Publications
… the USP II paddle method in an RC-6 dissolution test system. Accurately … solubility and
poor dissolution behavior of APZ drug (BDDCS-II drug), we examined the powder dissolution …
poor dissolution behavior of APZ drug (BDDCS-II drug), we examined the powder dissolution …
[PDF][PDF] Drug release profile of aripiprazole mouth dissolving polymeric formulation
… of aripiprazole, a poorly water soluble drug by forming dispersion with mannitol as water
soluble … Tablets were prepared by direct compression and Wet Granulation method. In both …
soluble … Tablets were prepared by direct compression and Wet Granulation method. In both …
Solubility of Aripiprazole in supercritical carbon dioxide: Experimental and modeling evaluations
E Ansari, B Honarvar, SA Sajadian, ZA Aboosadi… - 2023 - researchsquare.com
… solubility, and permeability of poorly water-soluble drugs is one of the major research topics
12. The dissolution … sc-CO2 solubility, in contrast, anti-solvent procedures are suitable for the …
12. The dissolution … sc-CO2 solubility, in contrast, anti-solvent procedures are suitable for the …
Specific and Sensitive RP-HPLC Method Development and Validation for the Determination of Aripiprazole: Application in Preformulation Screening of Nanoemulsion
SA Kumbhar, CR Kokare, B Shrivastava… - … : Recent Patents on …, 2020 - ingentaconnect.com
… solubility and bioavailability of aripiprazole by formulating a nanoemulsion. Due to course of
preformulation study, determination of solubility of aripiprazole … piprazole and dissolving in …
preformulation study, determination of solubility of aripiprazole … piprazole and dissolving in …
3D printed orodispersible films with Aripiprazole
W Jamróz, M Kurek, E Łyszczarz, J Szafraniec… - International journal of …, 2017 - Elsevier
… soluble substance such as aripiprazole seems to be extra advantageous in terms of dissolution
… the impact of the extrusion process and aripiprazole presence on the film properties. X-…
… the impact of the extrusion process and aripiprazole presence on the film properties. X-…
Impact of jet pulverization and wet milling techniques on properties of aripiprazole long-acting injection and absorption mechanism research in vivo
X Guo, M Zhang, Y Guo, H Liu, B Yang, J Gou… - International Journal of …, 2022 - Elsevier
… that aripiprazole monohydrate has lower solubility in water (… 10.0 g of crude aripiprazole was
dissolved in 200 mL of ethanol … milling process also played a role in the faster dissolution of …
dissolved in 200 mL of ethanol … milling process also played a role in the faster dissolution of …
Aripiprazole and Dehydro-Aripiprazole Solid Solutions: Crystalline Combinations of Drug and Active Metabolite in Tailored Compositions
JT Trotta, TA Zeidan, PA Tilak, BM Foxman… - Crystal Growth & …, 2020 - ACS Publications
… (APZ) and its active metabolite, dehydro-aripiprazole (dAPZ), … Dissolution studies of the
hydrated system demonstrated the … in APZ and dAPZ solubilities result in solid solution …
hydrated system demonstrated the … in APZ and dAPZ solubilities result in solid solution …
Enhancement of in vivo efficacy and oral bioavailability of aripiprazole with solid lipid nanoparticles
Silki, VR Sinha - AAPS PharmSciTech, 2018 - Springer
… Aripiprazole is a poorly soluble drug that, despite … dissolved in chloroform and subsequently
diluted with ethanol. The total drug content was estimated by UV spectrophotometric method …
diluted with ethanol. The total drug content was estimated by UV spectrophotometric method …
Morphological and crystalline transitions in monohydrous and anhydrous aripiprazole for a long-acting injectable suspension
X Tan, Y Zhong, L He, Y Zhang, G Jing, S Li, J Wang… - AAPS …, 2017 - Springer
… Many formulation and manufacturing processes can lead to … (APIs) such as solubility and
physical stability which influence … each tablet was exposed to the dissolution medium, 500 ml of …
physical stability which influence … each tablet was exposed to the dissolution medium, 500 ml of …