… equilibrium solubility and IDR. This study provided a valuable insight into the formation of
multicomponent pharmaceutical salts and presented potential alternative formulations of ARI. …

… solubility and bioavailability issues of poorly soluble active pharmaceutical ingredients (APIs).
Multicomponent crystalline solid forms of poorly soluble … have limited aqueous solubility [4]…

… of APZ such as solubility and dissolution profile were not … more crystalline phase space of
aripiprazole multicomponent … solubility of salt former the more soluble the multicomponent …

… \mathrm{multicomponent}\) crystallization from a stoichiometric … favors the corresponding
phase crystallization. Therefore, … single- and multicomponent crystal solubilities (equilibrium …

… Cocrystallization is an important route to tuning the solubility … The six multi-component
crystals all show high stability and … ARI 2 -RSV 1 ·MeOH crystallized in the Pn space group. The …

… of crystalline aripiprazole, they possessed higher solubility and … soluble inclusion compounds
of aripiprazole and HPBCD. … properties of the multi-component complexation technology, …

… rates, equilibrium solubility, chemical stability and mechanical properties by many folds. …
correlations in multi-component systems is more challenging because co-crystallizing systems …

… of solubility involves multicomponent amino acid systems along with cyclodextrin [1]. Aripiprazole
is … The SEM results in Figure 4 represent that the crystalline nature of the aripiprazole is …

… of its crystallization studies have focused on the development of cocrystals and multicomponent
… three times, and the average value was used to calculate the solubility. The mole fraction …

… The salts were prepared with solubilization-crystallization method. The salts were characterized
for pH-solubility, … pH-solubility profiles of the salts were similar to the drug except higher …