Development, characterisation and cytotoxicity studies of erlotinib entrapped gellan gum nanoparticles

S Sukumar, S Arockiasamy… - International Journal of …, 2022 - inderscienceonline.com
spectroscopy The fourier transform infrared analysis was carried out for gellan gum, pure
drug (erlotinib) and Gellan gum erlotinib (… determined using FTIR spectroscopy based on the …

… /aryl)‐3,4‐dihydro‐1′H,2H‐[3,4′‐bipyrazole]‐2‐carboxamides as EGFR kinase inhibitors: Synthesis, anticancer evaluation, and molecular docking studies

F Nawaz, O Alam, A Perwez, MA Rizvi… - Archiv der …, 2020 - Wiley Online Library
… The final structures were then characterized by Fourier-transform infrared spectroscopy (FT-…
± 0.54 µM which were compared with the standard drug erlotinib with IC 50 = 1.22 ± 0.03 µM …

[PDF][PDF] Total Structural Elucidation of Erlotinib and Gefitinib by Mainly 2D-Rotating Frame Overhauser Effect Spectroscopy (2D ROESY NMR)

C KARAASLAN, H GÖKER - Chemical Science, 2017 - avesis.ankara.edu.tr
Erlotinib and its HCl salt6-19. There are several reasons for this confusion. For example,
Erlotinib HCl should be the mixture of erlotinib … the commercially avaliable Erlotinib HCl sample …

Nanoparticle stabilizer as a determining factor of the drug/gold surface interaction: SERS and AFM-SEIRA studies

N Piergies, M Oćwieja, C Paluszkiewicz… - Applied Surface …, 2021 - Elsevier
erlotinib (drug applied in non-small-cell lung cancer therapy) on the investigated metal surface.
The surface-enhanced Raman spectroscopy (SERS) results for erlotinib … of erlotinib and …

Synthesis and biological assay of erlotinib analogues and BSA-conjugated erlotinib analogue

R Boobalan, KK Liu, JI Chao, C Chen - Bioorganic & Medicinal Chemistry …, 2017 - Elsevier
… model study for confirmation of attachment of small molecule to BSA. For this model study
(… 29 was used as it possess infrared spectroscopy detectable cyano group and its synthesis …

[HTML][HTML] Development of oral tablet formulation containing erlotinib: Randomly methylated-β-cyclodextrin inclusion complex using direct compression method

N Erdoğar - Turkish Journal of Pharmaceutical Sciences, 2021 - ncbi.nlm.nih.gov
… In vitro dissolution studies demonstrated the increase in aqueous solubility and dissolution
… this study applies an effective method of CD complexation to overcome limited drug solubility …

Time-staggered delivery of erlotinib and doxorubicin by gold nanocages with two smart polymers for reprogrammable release and synergistic with photothermal …

Y Feng, Y Cheng, Y Chang, H Jian, R Zheng, X Wu… - Biomaterials, 2019 - Elsevier
… Recently, it has been reported that cancer cells pretreated with epidermal growth factor
receptor (EGFR) inhibitor erlotinib (Erl) can significantly synergize its apoptosis against the DNA …

Folate-conjugated thermosensitive O-maleoyl modified chitosan micellar nanoparticles for targeted delivery of erlotinib

M Fathi, PS Zangabad, A Aghanejad, J Barar… - Carbohydrate …, 2017 - Elsevier
Erlotinib was synthesized in our laboratory as previously described (Asgari, Aghanejad,
& Mojarrad, 2011; Barghi, Aghanejad, Valizadeh, Barar, & Asgari, 2012). All other chemicals …

In vitro baselining of new pyrrolopyrimidine EGFR-TK inhibitors with Erlotinib

E Sundby, J Han, SJ Kaspersen, BH Hoff - European Journal of …, 2015 - Elsevier
… Lastly, as an indication of toxicity compounds 1 and 2 and Erlotinib were … studies Erlotinib
was found to possess slightly higher cell toxicity. Surprisingly, compound 2 was in this study

[HTML][HTML] Development and validation of RP-HPLC method for the estimation of Erlotinib in pharmaceutical formulation

ST Latha, SA Thangadurai, M Jambulingam… - Arabian journal of …, 2017 - Elsevier
… In this study, a simple, precise and accurate reverse phase high performance liquid
chromatography was developed for the estimation of Erlotinib in bulk and pharmaceutical dosage …