Investigating human disease using stem cell models
JL Sterneckert, P Reinhardt, HR Schöler - Nature Reviews Genetics, 2014 - nature.com
… Induced pluripotent stem cells (iPSCs) can be generated from specific patients with
known genotypes and observable phenotypes, and they are therefore ideally suited to …
known genotypes and observable phenotypes, and they are therefore ideally suited to …
Progress and prospects: stem cells and neurological diseases
S Gögel, M Gubernator, SL Minger - Gene therapy, 2011 - nature.com
… stem cells from patient's own skin and their subsequent differentiation into cell types lost by
neurodegenerative diseases … -made patient stem cells are used for cellular transplantation in …
neurodegenerative diseases … -made patient stem cells are used for cellular transplantation in …
Stem cells and neurological diseases
DC Hess, CV Borlongan - Cell proliferation, 2008 - Wiley Online Library
… In the early experience, patients with chronic progressive disease did not respond; this has
shifted the focus to patients with early disease, likely to have a major inflammatory component…
shifted the focus to patients with early disease, likely to have a major inflammatory component…
Collection of hematopoietic stem cells from patients with autoimmune diseases
… This paper summarizes a survey of 24 sites performing autologous hematopoietic stem
cell transplants for autoimmune diseases. The data were collected via retrospective survey …
cell transplants for autoimmune diseases. The data were collected via retrospective survey …
Induced pluripotent stem cells: the new patient?
… By using reprogrammed cells from patients disease models 'in a dish' are being developed,
allowing experiments that, until recently, would have been inconceivable. The concept of …
allowing experiments that, until recently, would have been inconceivable. The concept of …
[HTML][HTML] Disease-specific induced pluripotent stem cells
… induced pluripotent stem (iPS) cells from patients with a variety of genetic diseases with either
… Here, we report the derivation of human iPS cell lines from patients with a range of human …
… Here, we report the derivation of human iPS cell lines from patients with a range of human …
The clinical potential of stem cells
EA Mayhall, N Paffett-Lugassy, LI Zon - Current opinion in cell biology, 2004 - Elsevier
… tissues, can treat mouse disease models and human patients in which epithelial and neural
… stem cells in the clinic as a means for replacing cells that are damaged by disease or injury. …
… stem cells in the clinic as a means for replacing cells that are damaged by disease or injury. …
Stem cells applications in regenerative medicine and disease therapeutics
RS Mahla - International journal of cell biology, 2016 - Wiley Online Library
… the patient suffering from severe injuries or chronic disease. The spectacular progress in
the field of stem cell research has laid the foundation for cell based therapies of disease which …
the field of stem cell research has laid the foundation for cell based therapies of disease which …
Induced pluripotent stem cells as a model for accelerated patient-and disease-specific drug discovery
I Gunaseeli, MX Doss, C Antzelevitch… - Current medicinal …, 2010 - ingentaconnect.com
… replacement therapy is emerging as an innovative approach for the treatment of degenerative
cardiac diseases, and pluripotent stem cells appear to be an ideal source of cells in this …
cardiac diseases, and pluripotent stem cells appear to be an ideal source of cells in this …
[HTML][HTML] Stem cells: past, present, and future
W Zakrzewski, M Dobrzyński, M Szymonowicz… - Stem cell research & …, 2019 - Springer
… stem cells and the potential therapies based on these cells. The genesis of stem cells is followed
by laboratory steps of controlled stem … future life-threatening diseases of a given patient. …
by laboratory steps of controlled stem … future life-threatening diseases of a given patient. …
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