[HTML][HTML] Apolipoprotein E protects against bacterial lipopolysaccharide-induced lethality: a new therapeutic approach to treat gram-negative sepsis

M Van Oosten, PCN Rensen, ES Van Amersfoort… - Journal of Biological …, 2001 - ASBMB
… Lipopolysaccharide (LPS) is the primary mediator of Gram-negative sepsis by inducing the
… a physiological role in the protection against sepsis, and recombinant apoE may be used …

Therapeutic interventions in sepsis: current and anticipated pharmacological agents

P Shukla, GM Rao, G Pandey, S Sharma… - British journal of …, 2014 - Wiley Online Library
… After the withdrawal of recombinant human-activated protein C (rAPC), researchers and
physicians have continued to search for new therapeutic approaches and targets against sepsis, …

[HTML][HTML] Gender and sex hormones influence the response to trauma and sepsis: potential therapeutic approaches

MK Angele, MC Frantz, IH Chaudry - Clinics, 2006 - SciELO Brasil
SciELO - Brasil - Gender and sex hormones influence the response to trauma and sepsis:
potential therapeutic approaches Gender and sex hormones influence the response to trauma …

[HTML][HTML] Advances in sepsis therapy

T Glück, SM Opal - Drugs, 2004 - Springer
… of sepsis, several other adjuvant therapies for sepsis are in … of sepsis remains the mainstay
of therapy for severe sepsis. … into the standard treatment approach to sepsis remains to be …

New approaches to sepsis: molecular diagnostics and biomarkers

K Reinhart, M Bauer, NC Riedemann… - Clinical microbiology …, 2012 - Am Soc Microbiol
… Novel approaches to sepsis promise to transform sepsis from a physiologic syndrome into a
… help in the development of better diagnostic tools and effective adjunctive sepsis therapies. …

Therapeutic approaches targeting renin-angiotensin system in sepsis and its complications

L Ning, J Rong, Z Zhang, Y Xu - Pharmacological Research, 2021 - Elsevier
… To date, the current therapeutic approaches for sepsis are rapid control of infection and …
, was dramatically altered after sepsis, which allows us to treat sepsis from a neuroendocrine …

The apoptotic pathway as a therapeutic target in sepsis

DE Wesche-Soldato, RZ Swan, CS Chung… - Current drug …, 2007 - ingentaconnect.com
sepsis and clinical findings that support the hypothesis that apoptosis in the immune system
is a pathologic event in sepsis that can be a therapeutic … lymphocytes during sepsis may be …

Nucleic-acid based gene therapy approaches for sepsis

Y Hattori, K Hattori, T Suzuki, S Palikhe… - European Journal of …, 2018 - Elsevier
therapy may be considered to be a promising novel therapeutic approach for treatment of
sepsis… This review article provides an up-to-date summary of the gene-targeting approaches, …

[HTML][HTML] Therapeutic approaches in modulating the inflammatory and immunological response in patients with sepsis, acute respiratory distress syndrome, and …

Y Mehta, SB Dixit, K Zirpe, R Sud, PB Gopal, PA Koul… - Cureus, 2021 - ncbi.nlm.nih.gov
therapies such as CytoSorb and therapeutictherapeutics may be limited, we provide our
expert comments regarding immunomodulation to optimize outcomes in patients with sepsis

[HTML][HTML] Immunometabolism: another road to sepsis and its therapeutic targeting

V Kumar - Inflammation, 2019 - Springer
… dysregulated immune response during sepsis and plays a very … during sepsis to design
future target-based therapeuticssepsis and its targeting as a future therapeutic approach. …