Microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family.
TJ Hemesath, E Steingrimsson, G McGill… - … & development, 1994 - genesdev.cshlp.org
… The prospect that pigmentation enzymes and melanocyte survival … transcription factor
targets for the b-HLH-ZIP family. An understanding of the role of Mi in melanocyte development …
targets for the b-HLH-ZIP family. An understanding of the role of Mi in melanocyte development …
The transcription network regulating melanocyte development and melanoma
KW Vance, CR Goding - Pigment cell research, 2004 - Wiley Online Library
… IL6 signalling to the transcription factor STAT3, but how … family of transcription regulators in
melanocyte development or … such a variety of transcription factors regulating the melanocyte-…
melanocyte development or … such a variety of transcription factors regulating the melanocyte-…
[HTML][HTML] Transcription factors in melanocyte development: distinct roles for Pax-3 and Mitf
TJ Hornyak, DJ Hayes, LY Chiu, EB Ziff - Mechanisms of development, 2001 - Elsevier
… To assess the roles of the Pax-3 and Mitf transcription factors in melanocyte development,
we have utilized a transgenic mouse expressing β-galactosidase (lacZ) from the promoter of …
we have utilized a transgenic mouse expressing β-galactosidase (lacZ) from the promoter of …
Melanocytes and the Microphthalmia Transcription Factor Network
E Steingrímsson, NG Copeland, NA Jenkins - Annu. Rev. Genet., 2004 - annualreviews.org
… the Myc supergene family of bHLH-Zip transcription factors (68, 76). Proteins of this family all
… function as a master regulator of melanocyte development. This function is consistent with …
… function as a master regulator of melanocyte development. This function is consistent with …
Regulation of melanocyte pivotal transcription factor MITF by some other transcription factors
P Wan, Y Hu, L He - Molecular and cellular biochemistry, 2011 - Springer
… melanocytes and brain-derived melanocytes of the pigmented retinal epithelium [1, 2], is
pivotal in melanocyte development … -helix (bHLH) transcription factor family that is termed as E …
pivotal in melanocyte development … -helix (bHLH) transcription factor family that is termed as E …
[HTML][HTML] The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology
A Kawakami, DE Fisher - Laboratory investigation, 2017 - Elsevier
… transcription factor class. It regulates key genes for melanocyte development and differentiation.
MITF and other related family members, TFE3 and TFEB, together comprise the ‘MiT' …
MITF and other related family members, TFE3 and TFEB, together comprise the ‘MiT' …
The transcription factor Sox5 modulates Sox10 function during melanocyte development
CC Stolt, P Lommes, S Hillgärtner… - Nucleic acids …, 2008 - academic.oup.com
… Many transcription factors of the Sox protein family are widely expressed in the vertebrate
embryo and represent important developmental regulators ( 1 , 2 ). Several subgroups can be …
embryo and represent important developmental regulators ( 1 , 2 ). Several subgroups can be …
MITF: master regulator of melanocyte development and melanoma oncogene
C Levy, M Khaled, DE Fisher - Trends in molecular medicine, 2006 - cell.com
… transcription factors also function as translocated oncogenes in various human malignancies.
These data place MITF between instructing melanocytes … in melanocyte development and …
These data place MITF between instructing melanocytes … in melanocyte development and …
Microphthalamia-associated transcription factor: a critical regulator of pigment cell development and survival
HR Widlund, DE Fisher - Oncogene, 2003 - nature.com
… that encode a transcription factor of the basic-helix–loop–helix-leucine-zipper family (bHLHzip). …
During melanocyte development, additional key transcription factors include SOX10, an …
During melanocyte development, additional key transcription factors include SOX10, an …
Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor
K Opdecamp, A Nakayama, MTT Nguyen… - …, 1997 - journals.biologists.com
… factors are important for melanocyte development. Among the latter are mast cell growth factor
(Mgf), a polypep-tide growth factor … a member of a family of transcription factors known to …
(Mgf), a polypep-tide growth factor … a member of a family of transcription factors known to …
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