Developmental role of transcription factor isoforms generated by alternative splicing

AJ López - Developmental biology, 1995 - Elsevier
… The production of transcription factor isoforms by … Frequently, differences in biochemical
function among the isoforms can be … that may optimize or fine-tune transcription factor function in …

Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor

ZS Xiao, R Thomas, TK Hinson, LD Quarles - Gene, 1998 - Elsevier
… an osteoblast-specific transcription factor that regulates … identified in the mouse Cbfa1/Osf2
isoform. We found the novel 5… additional Cbfa1/Osf2 isoforms containing deletions of exons 1 …

Selective interaction of JNK protein kinase isoforms with transcription factors.

S Gupta, T Barrett, AJ Whitmarsh, J Cavanagh… - The EMBO …, 1996 - embopress.org
isoforms derived from the JNK1, JNK2 and JNK3 genes. The protein kinase activity of these
JNK isoforms was measured using the transcription factors … the JNK isoforms demonstrated …

[HTML][HTML] Complexity of translationally controlled transcription factor Sp3 isoform expression

A Sapetschnig, F Koch, G Rischitor, T Mennenga… - Journal of Biological …, 2004 - ASBMB
… Sp3 is a ubiquitous transcription factor closely related to Sp1. Both proteins contain a …
isoforms of Sp3 that retain different parts of the N terminus are expressed in vivo. The four isoforms

Transcription factor C/EBPβ isoform ratio regulates osteoclastogenesis through MafB

JJ Smink, V Begay, T Schoenmaker, E Sterneck… - The EMBO …, 2009 - embopress.org
… Here, we show that isoforms of the transcription factor CCAAT/… isoforms or that express only
the truncated LIP isoform. C/EBPβ‐deficient mice and mice that express the LIP isoform only (…

Regulation of transcription factor function by phosphorylation

AJ Whitmarsh, RJ Davis* - Cellular and Molecular Life Sciences CMLS, 2000 - Springer
isoform NF-ATc following its initial phosphorylation by an unknown kinase(s) [8], whereas the
NF-AT4 isoform … regulate the activities of transcription factors through multiple mechanisms. …

[HTML][HTML] Distinct spatial Ca2+ signatures selectively activate different NFAT transcription factor isoforms

P Kar, AB Parekh - Molecular cell, 2015 - cell.com
… related transcription factor isoforms, … isoform combinations as stimulus strength increases.
Our study uncovers a mechanism whereby co-existing cytoplasmic transcription factor isoforms

An isoform of transcription factor CREM expressed during spermatogenesis lacks the phosphorylation domain and represses cAMP-induced transcription.

WH Walker, BM Sanborn… - Proceedings of the …, 1994 - National Acad Sciences
… a role in transcriptional regulation during spermatogenesis. … transcription is via phosphorylation
by protein kinase A (PKA) of a single serine in the structurally similar transcription factors

The short isoform of NF-YA belongs to the embryonic stem cell transcription factor circuitry

D Dolfini, M Minuzzo, G Pavesi, R Mantovani - Stem Cells, 2012 - academic.oup.com
… ) is controlled at the transcriptional level by a handful of transcription factors (TFs) that promote
… We show that the levels of the short NF-YA isoform—NF-YAs—is high in mouse ESCs (…

Delta-lactoferrin, an intracellular lactoferrin isoform that acts as a transcription factor

C Mariller, S Hardivillé, E Hoedt… - … and Cell Biology, 2012 - cdnsciencepub.com
… It is an efficient transcription factor interacting in vivo via a DLf … transcription factor activity.
Our earlier investigations showed that O-GlcNAcylation negatively regulates DLf transcriptional